| Unique identifier for interactor A | uniprotkb:Q13586 |
| Unique identifier for interactor B | uniprotkb:Q96D31 |
| Alternative identifier for interactor A | intact:EBI-448878 uniprotkb:Q8N382 ensembl:ENSP00000300737.4 uniprotkb:E9PQJ4 |
| Alternative identifier for interactor B | intact:EBI-2291476 ensembl:ENSP00000482568.2 uniprotkb:Q3MHV3 uniprotkb:Q6DHX2 uniprotkb:Q96BP7 uniprotkb:Q96K71 |
| Aliases for A | psi-mi:stim1_human(display_long) uniprotkb:STIM1(gene name) psi-mi:STIM1(display_short) uniprotkb:GOK(gene name synonym) |
| Aliases for B | psi-mi:orai1_human(display_long) uniprotkb:ORAI1(gene name) psi-mi:ORAI1(display_short) uniprotkb:CRACM1(gene name synonym) uniprotkb:TMEM142A(gene name synonym) uniprotkb:Protein orai-1(gene name synonym) uniprotkb:Transmembrane protein 142A(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Balasuriya et al. (2014) |
| Identifier of the publication | pubmed:24996186 imex:IM-22938 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9631480 imex:IM-22938-2 |
| Confidence score | intact-miscore:0.96 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2a comment:"\"Cells were next co-transfected with DNA encoding Orai1-Myc/His and HA-STIM1. The localization of the two proteins, with and without thapsigargin (5 M) treatment, was determined by immunofluorescence analysis of saponin-permeabilized cells. In control cells, Orai1 was seen predominantly at the plasma membrane, whereas STIM1 was found in a reticular pattern throughout the cell cytoplasm, consistent with an ER localization (Fig. 2A). By contrast, in thapsigargin-treated cells, the STIM1 and Orai1 signals overlapped extensively, consistent with the translocation of STIM1 to sites beneath the plasma membrane\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-tsa201) taxid:9606(Homo sapiens tsa201 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2014/06/23 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? |
| Feature(s) for interactor B | tandem tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag immunostaining |
| Participant identification method for interactor B | Anti tag immunostaining |