| Unique identifier for interactor A | uniprotkb:Q05655 |
| Unique identifier for interactor B | uniprotkb:C6GKH1 |
| Alternative identifier for interactor A | intact:EBI-704279 uniprotkb:B2R834 uniprotkb:Q86XJ6 uniprotkb:Q15144 uniprotkb:B0KZ81 ensembl:ENSP00000331602.3 ensembl:ENSP00000378217.2 ensembl:ENSP00000498400.1 ensembl:ENSP00000498623.1 ensembl:ENSP00000499558.1 |
| Alternative identifier for interactor B | intact:EBI-9547476 ensembl:ENSP00000436937.1 ensembl:ENSP00000479701.1 |
| Aliases for A | psi-mi:kpcd_human(display_long) uniprotkb:nPKC-delta(gene name synonym) uniprotkb:PRKCD(gene name) psi-mi:PRKCD(display_short) uniprotkb:Tyrosine-protein kinase PRKCD(gene name synonym) uniprotkb:PKCD(gene name synonym) |
| Aliases for B | psi-mi:c6gkh1_human(display_long) uniprotkb:IL32(gene name) psi-mi:IL32(display_short) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Kim et al. (2014) |
| Identifier of the publication | pubmed:24996056 imex:IM-22926 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9547473 imex:IM-22926-1 |
| Confidence score | intact-miscore:0.46 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f4a f4c f4d f4e f5b comment:"\"We observed that IL-32ζ interacted with PMAactivated novel PKCs (PKCδ and PKCε), among other PKC isoforms (Fig. 4A). Above all, IL-32ζ was mainly bound to PKCδ, and this interaction was bilaterally confirmed by immunoprecipitation using anti-6x Myc-antibody and anti-5x FLAG-antibody (Fig. 4B, C). Moreover, this interaction was blocked by rottlerin, a PKCδ specific inhibitor, and Gö6850, a nonspecific PKC inhibitor, but not Gö6976, a classical PKC inhibitor (Fig. 4D).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2014/06/05 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:?-? binding-associated region:1-335 |
| Feature(s) for interactor B | myc tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |