Curation Details
Interaction ID: IM-22917-7

Unique identifier for interactor Auniprotkb:Q9Y281
Unique identifier for interactor Buniprotkb:P50461
Alternative identifier for interactor Aintact:EBI-351218
uniprotkb:G3V5P4
ensembl:ENSP00000298159.6
ensembl:ENSP00000340635.3
ensembl:ENSP00000500375.1
ensembl:ENSP00000500532.1
Alternative identifier for interactor Bintact:EBI-5658719
uniprotkb:Q9P131
intact:EBI-9540516
uniprotkb:S4S7M7
ensembl:ENSP00000265968.3
ensembl:ENSP00000431813.1
ensembl:ENSP00000497388.1
Aliases for Apsi-mi:cof2_human(display_long)
uniprotkb:CFL2(gene name)
psi-mi:CFL2(display_short)
uniprotkb:Cofilin, muscle isoform(gene name synonym)
Aliases for Bpsi-mi:csrp3_human(display_long)
uniprotkb:CLP(gene name synonym)
uniprotkb:Cardiac LIM protein(gene name synonym)
uniprotkb:Cysteine-rich protein 3(gene name synonym)
uniprotkb:LIM domain protein, cardiac(gene name synonym)
uniprotkb:MLP(gene name synonym)
uniprotkb:Muscle LIM protein(gene name synonym)
uniprotkb:CSRP3(gene name)
psi-mi:CSRP3(display_short)
Interaction detection methodspsi-mi:"MI:0047"(far western blotting)
First authorVafiadaki et al. (2014)
Identifier of the publicationpubmed:24860983
imex:IM-22917
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9539964
imex:IM-22917-7
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6h f6i
comment:"\"we performed competition assays by blot overlay using His-CFL2 and MBP-MLP-a in the presence or absence of the GST-MLP-b. The MLP/CFL2 interaction remained unaffected by the presence of the MLP-b, indicating that the latter does not compete with CFL2 for binding to full length MLP (Fig. 6H-I).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/05/23
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?
Feature(s) for interactor Bmaltose binding protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BAnti tag western blot