Curation Details
Interaction ID: IM-22738-1

Unique identifier for interactor Auniprotkb:P04296
Unique identifier for interactor Buniprotkb:P43246
Alternative identifier for interactor Aintact:EBI-7184583
intact:MINT-191337
uniprotkb:B9VQF7
uniprotkb:Q09IA4
Alternative identifier for interactor Bintact:EBI-355888
uniprotkb:B4E2Z2
ensembl:ENSP00000233146.2
uniprotkb:O75488
Aliases for Apsi-mi:dnbi_hhv11(display_long)
uniprotkb:DBP(gene name)
psi-mi:DBP(display_short)
uniprotkb:ICP8(gene name synonym)
uniprotkb:UL29(orf name)
Aliases for Bpsi-mi:msh2_human(display_long)
uniprotkb:MSH2(gene name)
psi-mi:MSH2(display_short)
uniprotkb:MutS protein homolog 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorTaylor et al. (2004)
Identifier of the publicationpubmed:15140983
mint:MINT-6692522
doi:10.1128/JVI.78.11.5856-5866.2004
imex:IM-22738
NCBI Taxonomy identifier for interactor Ataxid:10299(hhv11)
taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9631489
imex:IM-22738-1
Confidence scoreintact-miscore:0.43
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1 t1
comment:"\"The IPs were separated by SDS-PAGE, and the resolved proteins were visualized by Coomassie blue staining (Fig. 1A). Protein bands present only in IPs from virus-infected cells were excised, digested with trypsin, and analyzed by tandem MS. We identified, in total, over 50 cellular and viral proteins that coprecipitated with ICP8 with 39S antibody (Table 1).\""
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hep2)
taxid:9606(Homo sapiens HeLa HEp-2 epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2008/07/29
Update date2017/02/23
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BIdentification by mass spectrometry