Curation Details
Interaction ID: IM-22623-6

Unique identifier for interactor Auniprotkb:P09917
Unique identifier for interactor Buniprotkb:Q13555
Alternative identifier for interactor Aintact:EBI-79934
uniprotkb:Q5JQ14
uniprotkb:E5FPY5
uniprotkb:E5FPY7
uniprotkb:E5FPY8
uniprotkb:B7ZLS0
ensembl:ENSP00000363512.2
ensembl:ENSP00000484468.1
Alternative identifier for interactor Bintact:EBI-1383465
uniprotkb:O00561
uniprotkb:Q5SWX4
uniprotkb:Q8NIA4
uniprotkb:O15378
uniprotkb:Q13556
uniprotkb:Q5SQZ3
uniprotkb:Q5SQZ4
uniprotkb:Q8N4I3
uniprotkb:Q13279
uniprotkb:Q13282
uniprotkb:Q7KYX5
uniprotkb:A0A0A0MS52
uniprotkb:A0A0A0MT11
Aliases for Apsi-mi:lox5_human(display_long)
uniprotkb:ALOX5(gene name)
psi-mi:ALOX5(display_short)
uniprotkb:LOG5(gene name synonym)
uniprotkb:Arachidonate 5-lipoxygenase(gene name synonym)
Aliases for Bpsi-mi:kcc2g_human(display_long)
uniprotkb:CAMK(gene name synonym)
uniprotkb:CAMK-II(gene name synonym)
uniprotkb:CAMK2G(gene name)
psi-mi:CAMK2G(display_short)
uniprotkb:CAMKG(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorMarkoutsa et al. (2014)
Identifier of the publicationpubmed:24860872
imex:IM-22623
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9207248
imex:IM-22623-6
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 3b
comment:"\"After in-vitro kinase assay with CaMK II and 5-LO, gel based MS analysis failed to detect any phosphopeptide. However, this is in contrast with immunoblotting experiments which indicated phosphorylation of 5-LO at both Ser271 and Ser523 (Fig. 3).\""
causality statement:Q13555 is required for phosphorylation of P09917
resulting-ptm:P09917 Ser-271 and Ser-523 O-phospho-L-serine
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/02/17
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Aphosphorylated residue:523-523
phosphorylated residue:271-271
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BPredetermined participant