Curation Details
Interaction ID: IM-22623-4

Unique identifier for interactor Auniprotkb:P08631
Unique identifier for interactor Buniprotkb:P09917
Alternative identifier for interactor Aintact:EBI-346340
uniprotkb:E1P5M2
uniprotkb:A8K1I1
ensembl:ENSP00000365012.3
uniprotkb:Q29RX1
uniprotkb:Q2VPE2
uniprotkb:Q504R5
uniprotkb:Q5T7K1
uniprotkb:Q5T7K2
uniprotkb:Q96CC0
uniprotkb:Q9H5Y5
uniprotkb:Q9NUA4
uniprotkb:Q9UMJ5
uniprotkb:B4DQB6
Alternative identifier for interactor Bintact:EBI-79934
uniprotkb:B7ZLS0
ensembl:ENSP00000363512.2
ensembl:ENSP00000484468.1
uniprotkb:Q5JQ14
uniprotkb:E5FPY5
uniprotkb:E5FPY7
uniprotkb:E5FPY8
Aliases for Apsi-mi:hck_human(display_long)
uniprotkb:HCK(gene name)
psi-mi:HCK(display_short)
uniprotkb:Hemopoietic cell kinase(gene name synonym)
uniprotkb:p59-HCK/p60-HCK(gene name synonym)
uniprotkb:Hematopoietic cell kinase(gene name synonym)
uniprotkb:p59Hck(gene name synonym)
uniprotkb:p61Hck(gene name synonym)
Aliases for Bpsi-mi:lox5_human(display_long)
uniprotkb:ALOX5(gene name)
psi-mi:ALOX5(display_short)
uniprotkb:LOG5(gene name synonym)
uniprotkb:Arachidonate 5-lipoxygenase(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorMarkoutsa et al. (2014)
Identifier of the publicationpubmed:24860872
imex:IM-22623
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9207213
imex:IM-22623-4
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Table 2
causality statement:P08631 is required for phosphorylation of P09917
resulting-ptm:P09919 Tyr-42, Tyr-53 an Tyr-94 O4'-phospho-L-tyrosine
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/02/17
Update date2014/10/27
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bphosphorylated residue:42-42
phosphorylated residue:94-94
phosphorylated residue:53-53
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BIdentification by mass spectrometry