Curation Details
Interaction ID: IM-22623-3

Unique identifier for interactor Auniprotkb:P09769
Unique identifier for interactor Buniprotkb:P09917
Alternative identifier for interactor Aintact:EBI-1383732
uniprotkb:Q9UIQ3
uniprotkb:D3DPL7
ensembl:ENSP00000363115.3
ensembl:ENSP00000363116.1
ensembl:ENSP00000363117.3
ensembl:ENSP00000382126.1
Alternative identifier for interactor Bintact:EBI-79934
uniprotkb:Q5JQ14
uniprotkb:E5FPY5
uniprotkb:E5FPY7
uniprotkb:E5FPY8
uniprotkb:B7ZLS0
ensembl:ENSP00000363512.2
ensembl:ENSP00000484468.1
Aliases for Apsi-mi:fgr_human(display_long)
uniprotkb:SRC2(gene name synonym)
uniprotkb:Proto-oncogene c-Fgr(gene name synonym)
uniprotkb:FGR(gene name)
psi-mi:FGR(display_short)
uniprotkb:p55-Fgr(gene name synonym)
uniprotkb:"Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog"(gene name synonym)
uniprotkb:p58-Fgr(gene name synonym)
uniprotkb:p58c-Fgr(gene name synonym)
Aliases for Bpsi-mi:lox5_human(display_long)
uniprotkb:ALOX5(gene name)
psi-mi:ALOX5(display_short)
uniprotkb:LOG5(gene name synonym)
uniprotkb:Arachidonate 5-lipoxygenase(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorMarkoutsa et al. (2014)
Identifier of the publicationpubmed:24860872
imex:IM-22623
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9207193
imex:IM-22623-3
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Table 2
causality statement:P09769 is required for phosphorylation of P09917
resulting-ptm:P09917 Tyr-42, Tyr-53 and Tyr-445 O4'-phospho-L-tyrosine
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/02/17
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bphosphorylated residue:42-42
phosphorylated residue:53-53
phosphorylated residue:445-445
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BIdentification by mass spectrometry