Curation Details
Interaction ID: IM-22605-1

Unique identifier for interactor Auniprotkb:P20807
Unique identifier for interactor Buniprotkb:P20807
Alternative identifier for interactor Aintact:EBI-5655000
ensembl:ENSP00000380349.3
uniprotkb:Q9Y5S6
uniprotkb:Q9Y5S7
uniprotkb:Q9BTU4
uniprotkb:A6H8K6
uniprotkb:Q7L4R0
uniprotkb:Q9BQC8
Alternative identifier for interactor Bintact:EBI-5655000
ensembl:ENSP00000380349.3
uniprotkb:Q9Y5S6
uniprotkb:Q9Y5S7
uniprotkb:Q9BTU4
uniprotkb:A6H8K6
uniprotkb:Q7L4R0
uniprotkb:Q9BQC8
Aliases for Apsi-mi:can3_human(display_long)
uniprotkb:CANP3(gene name synonym)
uniprotkb:CANPL3(gene name synonym)
uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)
uniprotkb:Calpain L3(gene name synonym)
uniprotkb:Calpain p94(gene name synonym)
uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)
uniprotkb:NCL1(gene name synonym)
uniprotkb:New calpain 1(gene name synonym)
uniprotkb:CAPN3(gene name)
psi-mi:CAPN3(display_short)
Aliases for Bpsi-mi:can3_human(display_long)
uniprotkb:CANP3(gene name synonym)
uniprotkb:CANPL3(gene name synonym)
uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)
uniprotkb:Calpain L3(gene name synonym)
uniprotkb:Calpain p94(gene name synonym)
uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)
uniprotkb:NCL1(gene name synonym)
uniprotkb:New calpain 1(gene name synonym)
uniprotkb:CAPN3(gene name)
psi-mi:CAPN3(display_short)
Interaction detection methodspsi-mi:"MI:0114"(x-ray crystallography)
First authorPartha et al. (2014)
Identifier of the publicationpubmed:24846670
imex:IM-22605
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9525089
imex:IM-22605-1
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2 f3 f4 f5 t1
comment:"\"The resulting electron density map showed three calpain-3 PEF domain chains in the asymmetric unit. Chains A and B form one homodimer unit (Figure 2A), while chain C dimerizes with a symmetry-related molecule via a crystallographic 2-fold axis.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/05/14
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:650-821
Feature(s) for interactor Bbinding-associated region:650-821
Stoichiometry for interactor A2
Stoichiometry for interactor B0
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant