Curation Details
Interaction ID: IM-22603-6

Unique identifier for interactor Auniprotkb:Q93009
Unique identifier for interactor Buniprotkb:P06400
Alternative identifier for interactor Aintact:EBI-302474
uniprotkb:B7Z815
uniprotkb:H0Y3G8
ensembl:ENSP00000343535.4
uniprotkb:A6NMY8
intact:EBI-28988230
Alternative identifier for interactor Bintact:EBI-491274
uniprotkb:A8K5E3
ensembl:ENSP00000267163.4
uniprotkb:P78499
uniprotkb:Q5VW46
uniprotkb:Q8IZL4
Aliases for Apsi-mi:ubp7_human(display_long)
uniprotkb:USP7(gene name)
psi-mi:USP7(display_short)
uniprotkb:HAUSP(gene name synonym)
uniprotkb:Ubiquitin thioesterase 7(gene name synonym)
uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)
uniprotkb:Deubiquitinating enzyme 7(gene name synonym)
uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym)
Aliases for Bpsi-mi:rb_human(display_long)
uniprotkb:pRb(gene name synonym)
uniprotkb:pp110(gene name synonym)
uniprotkb:p105-Rb(gene name synonym)
uniprotkb:RB1(gene name)
psi-mi:RB1(display_short)
uniprotkb:p110-RB1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorBhattacharya et al. (2014)
Identifier of the publicationimex:IM-22603
pubmed:24823443
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9521876
imex:IM-22603-6
Confidence scoreintact-miscore:0.57
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2d
comment:"\"Confocal images from ICC in HEK293 cells show abundant yellow spots revealing that indeed HAUSP and Rb colocalize (Fig. 2A). Again, similar data was found when ICC was done in COS-7 cells (Fig. S4).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2014/05/12
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot