Curation Details
Interaction ID: IM-22599-2

Unique identifier for interactor Auniprotkb:P62380
Unique identifier for interactor Buniprotkb:P52655
Alternative identifier for interactor Aintact:EBI-716225
uniprotkb:O95753
uniprotkb:Q9BWD5
uniprotkb:Q9Z2Z0
uniprotkb:A8K8F5
ensembl:ENSP00000237264.3
ensembl:ENSP00000478795.1
Alternative identifier for interactor Bintact:EBI-389518
uniprotkb:Q3KNQ9
ensembl:ENSP00000452454.1
Aliases for Apsi-mi:tbpl1_human(display_long)
uniprotkb:TATA box-binding protein-related factor 2(gene name synonym)
uniprotkb:TLF(gene name synonym)
uniprotkb:21 kDa TBP-like protein(gene name synonym)
uniprotkb:TBPL1(gene name)
psi-mi:TBPL1(display_short)
uniprotkb:TLP(gene name synonym)
uniprotkb:TLP21(gene name synonym)
uniprotkb:TRF2(gene name synonym)
uniprotkb:TRP(gene name synonym)
uniprotkb:TBP-related protein(gene name synonym)
uniprotkb:TBP-like factor(gene name synonym)
uniprotkb:Second TBP of unique DNA protein(gene name synonym)
Aliases for Bpsi-mi:tf2aa_human(display_long)
uniprotkb:GTF2A1(gene name)
psi-mi:GTF2A1(display_short)
uniprotkb:TF2A1(gene name synonym)
uniprotkb:General transcription factor IIA subunit 1(gene name synonym)
uniprotkb:Transcription initiation factor TFIIA 42 kDa subunit(gene name synonym)
uniprotkb:TFIIAL(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorSuzuki et al. (2014)
Identifier of the publicationpubmed:24835508
imex:IM-22599
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9524891
imex:IM-22599-2
Confidence scoreintact-miscore:0.85
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6f
comment:"\"We then examined effect of etoposide on TLP-TFIIA interaction. A co-immunoprecipitation experiment revealed that TLP and TFIIA form an intracellular complex in etoposide-treated cells upon DNA damage (Fig. 6F).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hct116)
taxid:9606(Homo sapiens HCT116 colon carcinoma cell)
Parameters of the interaction-
Creation date2014/05/13
Update date2025/01/04
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot