Curation Details
Interaction ID: IM-22595-2

Unique identifier for interactor Auniprotkb:P78380
Unique identifier for interactor Buniprotkb:P17987
Alternative identifier for interactor Aintact:EBI-7151999
ensembl:ENSP00000309124.3
uniprotkb:G3V1I4
uniprotkb:Q2PP00
intact:MINT-1343572
uniprotkb:Q7Z484
uniprotkb:B4DI48
uniprotkb:A8K7V9
Alternative identifier for interactor Bintact:EBI-356553
uniprotkb:E1P5B2
ensembl:ENSP00000317334.7
uniprotkb:Q15556
uniprotkb:Q5TCM3
Aliases for Apsi-mi:olr1_human(display_long)
uniprotkb:OLR1(gene name)
psi-mi:OLR1(display_short)
uniprotkb:LOX1(gene name synonym)
uniprotkb:Lectin-type oxidized LDL receptor 1(gene name synonym)
uniprotkb:Lectin-like oxidized LDL receptor 1(gene name synonym)
uniprotkb:CLEC8A(gene name synonym)
uniprotkb:C-type lectin domain family 8 member A(gene name synonym)
Aliases for Bpsi-mi:tcpa_human(display_long)
uniprotkb:CCTA(gene name synonym)
uniprotkb:TCP1(gene name)
psi-mi:TCP1(display_short)
uniprotkb:CCT1(gene name synonym)
uniprotkb:CCT-alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorBakthavatsalam et al. (2014)
Identifier of the publicationimex:IM-22595
pubmed:24846140
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9518189
imex:IM-22595-2
Confidence scoreintact-miscore:0.64
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3b f5b
comment:"\"Western blot analysis showed that CCT1 coimmunoprecipitated with LOX-1 in untreated cells but not inOxLDL-treated cells (Fig. 5B). Thus, our findings indicate that OxLDL suppressed the CCT interaction with LOX-1.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-uvec)
taxid:9606(Homo sapiens umbilical vein endotheliium)
Parameters of the interaction-
Creation date2014/05/06
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot