Curation Details
Interaction ID: IM-22589-2

Unique identifier for interactor Auniprotkb:P06241
Unique identifier for interactor Buniprotkb:P04626
Alternative identifier for interactor Aintact:EBI-515315
uniprotkb:B5BU57
intact:EBI-2561531
uniprotkb:E1P557
uniprotkb:H0UI48
ensembl:ENSP00000346671.3
ensembl:ENSP00000357656.2
uniprotkb:Q16248
uniprotkb:Q5R3A6
uniprotkb:Q5R3A7
uniprotkb:Q8N5D7
Alternative identifier for interactor Bintact:EBI-641062
uniprotkb:B2RZG3
uniprotkb:B4DHN3
uniprotkb:X5D2V5
ensembl:ENSP00000269571.4
uniprotkb:Q14256
uniprotkb:Q6LDV1
uniprotkb:Q9UMK4
Aliases for Apsi-mi:fyn_human(display_long)
uniprotkb:p59-Fyn(gene name synonym)
uniprotkb:Proto-oncogene c-Fyn(gene name synonym)
uniprotkb:Src-like kinase(gene name synonym)
uniprotkb:FYN(gene name)
psi-mi:FYN(display_short)
uniprotkb:Proto-oncogene Syn(gene name synonym)
Aliases for Bpsi-mi:erbb2_human(display_long)
uniprotkb:p185erbB2(gene name synonym)
uniprotkb:MLN19(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)
uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)
uniprotkb:Proto-oncogene Neu(gene name synonym)
uniprotkb:ERBB2(gene name)
psi-mi:ERBB2(display_short)
uniprotkb:HER2(gene name synonym)
uniprotkb:NEU(gene name synonym)
uniprotkb:NGL(gene name synonym)
uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0107"(surface plasmon resonance)
First authorBornet et al. (2014)
Identifier of the publicationimex:IM-22589
pubmed:24815698
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9396619
imex:IM-22589-2
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2b
comment:"\"The fast exchange observed between the free and bound forms were in agreement with a KD of 0.935 mM as determined by NMR and of 0.909 mM as determined by surface plasmon resonance experiments (Figure 2).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:0.909x10^-3(molar)
Creation date2014/04/23
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:82-143
Feature(s) for interactor Bbinding-associated region:1146-1154
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPeptide synthesis