| Unique identifier for interactor A | uniprotkb:P05067 |
| Unique identifier for interactor B | uniprotkb:P05067 |
| Alternative identifier for interactor A | intact:EBI-77613 uniprotkb:P09000 uniprotkb:P78438 uniprotkb:Q13764 uniprotkb:Q13778 uniprotkb:Q13793 intact:EBI-28985182 uniprotkb:Q6GSC0 uniprotkb:Q8WZ99 uniprotkb:Q9UC33 uniprotkb:Q9UCC8 uniprotkb:Q9UCD1 uniprotkb:Q9UQ58 uniprotkb:Q16011 uniprotkb:Q16014 uniprotkb:Q16019 uniprotkb:Q16020 uniprotkb:Q9BT38 uniprotkb:Q9UCA9 uniprotkb:Q9UCB6 uniprotkb:B4DII8 uniprotkb:B2R5V1 uniprotkb:D3DSD1 uniprotkb:D3DSD2 uniprotkb:D3DSD3 ensembl:ENSP00000284981.4 |
| Alternative identifier for interactor B | intact:EBI-77613 uniprotkb:P09000 uniprotkb:P78438 uniprotkb:Q13764 uniprotkb:Q13778 uniprotkb:Q13793 intact:EBI-28985182 uniprotkb:Q6GSC0 uniprotkb:Q8WZ99 uniprotkb:Q9UC33 uniprotkb:Q9UCC8 uniprotkb:Q9UCD1 uniprotkb:Q9UQ58 uniprotkb:Q16011 uniprotkb:Q16014 uniprotkb:Q16019 uniprotkb:Q16020 uniprotkb:Q9BT38 uniprotkb:Q9UCA9 uniprotkb:Q9UCB6 uniprotkb:B4DII8 uniprotkb:B2R5V1 uniprotkb:D3DSD1 uniprotkb:D3DSD2 uniprotkb:D3DSD3 ensembl:ENSP00000284981.4 |
| Aliases for A | psi-mi:a4_human(display_long) uniprotkb:APP(gene name) psi-mi:APP(display_short) uniprotkb:A4(gene name synonym) uniprotkb:AD1(gene name synonym) uniprotkb:Alzheimer disease amyloid protein(gene name synonym) uniprotkb:ABPP(gene name synonym) uniprotkb:PreA4(gene name synonym) uniprotkb:Cerebral vascular amyloid peptide(gene name synonym) uniprotkb:Protease nexin-II(gene name synonym) uniprotkb:APPI(gene name synonym) uniprotkb:Amyloid precursor protein(gene name synonym) uniprotkb:Amyloid-beta A4 protein(gene name synonym) uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym) uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym) |
| Aliases for B | psi-mi:a4_human(display_long) uniprotkb:APP(gene name) psi-mi:APP(display_short) uniprotkb:A4(gene name synonym) uniprotkb:AD1(gene name synonym) uniprotkb:Alzheimer disease amyloid protein(gene name synonym) uniprotkb:ABPP(gene name synonym) uniprotkb:PreA4(gene name synonym) uniprotkb:Cerebral vascular amyloid peptide(gene name synonym) uniprotkb:Protease nexin-II(gene name synonym) uniprotkb:APPI(gene name synonym) uniprotkb:Amyloid precursor protein(gene name synonym) uniprotkb:Amyloid-beta A4 protein(gene name synonym) uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym) uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0030"(cross-linking study) |
| First author | Chang et al. (2014) |
| Identifier of the publication | imex:IM-22567 pubmed:24720730 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9353169 imex:IM-22567-13 |
| Confidence score | intact-miscore:0.99 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f4 comment:"\"To characterize the oligomer assembly, we used Western blot analysis to examine the Aβ mixing ratios (Figure 4). We collected the time points at 0, 6, 80, and 104 hr incubation (Figure 4a) based on the fact that the oligomer peak of Aβ42 alone in SEC showed significant decrease after 104 hr. To avoid SDS denaturation of the Aβ assembly, we also adopted the PICUP assay [37] to cross-link the assemblies before performing western blotting (Figure 4b).\"" dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/04/04 |
| Update date | 2024/11/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:672-713 |
| Feature(s) for interactor B | binding-associated region:672-711 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |