| Unique identifier for interactor A | uniprotkb:Q05513 |
| Unique identifier for interactor B | uniprotkb:P41743 |
| Alternative identifier for interactor A | intact:EBI-295351 uniprotkb:Q15207 uniprotkb:Q5SYT5 uniprotkb:Q969S4 uniprotkb:A8K4N0 uniprotkb:A8MU64 ensembl:ENSP00000367830.3 uniprotkb:B7Z2J7 uniprotkb:E9PCW2 |
| Alternative identifier for interactor B | intact:EBI-286199 uniprotkb:Q8WW06 uniprotkb:D3DNQ4 ensembl:ENSP00000295797.4 |
| Aliases for A | psi-mi:kpcz_human(display_long) uniprotkb:PRKCZ(gene name) psi-mi:PRKCZ(display_short) uniprotkb:PKC2(gene name synonym) uniprotkb:nPKC-zeta(gene name synonym) |
| Aliases for B | psi-mi:kpci_human(display_long) uniprotkb:nPKC-iota(gene name synonym) uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym) uniprotkb:PRKCI(gene name) psi-mi:PRKCI(display_short) uniprotkb:DXS1179E(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Li et al. (2014) |
| Identifier of the publication | pubmed:24375676 imex:IM-22242 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9253610 imex:IM-22242-4 |
| Confidence score | intact-miscore:0.89 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:sf1c comment:"\"Since PKCι, another member of the atypical PKC family, is highly homologous to PKCζ, we also determined if PKCι TM is phosphorylated by mTORC2. Similar to PKCζ, the TM phosphorylation of PKCι was completely lost in mTOR inhibitor‐treated 293T cells whereas the A‐loop was not affected (supplementary Fig S1C). Thus, PKCι TM (T564 in human PKCι) is also a substrate of mTORC2.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens HEK293T embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2014/03/05 |
| Update date | 2024/11/07 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |