| Unique identifier for interactor A | uniprotkb:P10997 |
| Unique identifier for interactor B | uniprotkb:P10997 |
| Alternative identifier for interactor A | intact:EBI-8526679 uniprotkb:Q14598 intact:MINT-8074874 uniprotkb:Q0ZD87 ensembl:ENSP00000240652.3 ensembl:ENSP00000437357.1 |
| Alternative identifier for interactor B | intact:EBI-8526679 uniprotkb:Q14598 intact:MINT-8074874 uniprotkb:Q0ZD87 ensembl:ENSP00000240652.3 ensembl:ENSP00000437357.1 |
| Aliases for A | psi-mi:iapp_human(display_long) uniprotkb:IAPP(gene name) psi-mi:IAPP(display_short) uniprotkb:Amylin(gene name synonym) uniprotkb:Diabetes-associated peptide(gene name synonym) uniprotkb:Insulinoma amyloid peptide(gene name synonym) |
| Aliases for B | psi-mi:iapp_human(display_long) uniprotkb:IAPP(gene name) psi-mi:IAPP(display_short) uniprotkb:Amylin(gene name synonym) uniprotkb:Diabetes-associated peptide(gene name synonym) uniprotkb:Insulinoma amyloid peptide(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0038"(dynamic light scattering) |
| First author | Wang et al. (2014) |
| Identifier of the publication | imex:IM-22231 pubmed:24561193 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9119389 imex:IM-22231-3 |
| Confidence score | intact-miscore:0.95 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2 comment:"\"In order to confirm the difference in the dimensions of the aggregate species of hIAPP in bulk solution with and without inhibitor, we measured the size population in the process of hIAPP aggregation by the dynamic light scattering (DLS) experiments in both cases (Figure 2). In the absence of inhibitor, the growth of hIAPP particles from hydrodynamic diameter (d) of several nanometers (monomers) to several micrometers via intermediates with d smaller than 400 nm was clearly observed, along with the broadening of size distribution. In comparison with the case of hIAPP alone in bulk solution, the growth of the peptide in the presence of equimolar inhibitor stopped at ~2 h with a narrower population of d around 200-350 nm.\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/02/06 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |