Curation Details
Interaction ID: IM-22213-3

Unique identifier for interactor Auniprotkb:P36776
Unique identifier for interactor Buniprotkb:P02666
Alternative identifier for interactor Aintact:EBI-357448
intact:EBI-1054513
uniprotkb:D6W635
uniprotkb:E5KMH8
uniprotkb:P36777
uniprotkb:Q8N8K8
uniprotkb:Q9UQ95
ensembl:ENSP00000353826.2
uniprotkb:B3KPH8
uniprotkb:F5GZ27
intact:EBI-10964236
Alternative identifier for interactor Bintact:EBI-5260183
uniprotkb:A1YQZ8
uniprotkb:A6N8V0
uniprotkb:Q2TA13
uniprotkb:Q5EEQ6
uniprotkb:Q5EEQ7
uniprotkb:Q6UN63
uniprotkb:Q9BDG5
uniprotkb:Q9TSD5
Aliases for Apsi-mi:lonm_human(display_long)
uniprotkb:LONHs(gene name synonym)
uniprotkb:PRSS15(gene name synonym)
uniprotkb:LONP1(gene name)
psi-mi:LONP1(display_short)
uniprotkb:Lon protease-like protein(gene name synonym)
uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)
uniprotkb:Serine protease 15(gene name synonym)
Aliases for Bpsi-mi:casb_bovin(display_long)
uniprotkb:CSN2(gene name)
psi-mi:CSN2(display_short)
Interaction detection methodspsi-mi:"MI:0435"(protease assay)
First authorAmbro et al. (2014)
Identifier of the publicationpubmed:24520911
imex:IM-22213
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9913(bovin)
taxid:9913("Bos taurus (Bovine)")
Interaction typespsi-mi:"MI:0194"(cleavage reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9107892
imex:IM-22213-3
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3 t1
comment:"\"In contrast to the ATPase activity, the protease activity could be classified into only two general groups: either a mutant possessed ≥75% of the wild-type activity (G893A, G894A, G894S, G893A-G894A, W770A), or it possessed little to no activity (G894P, G893A-G894P, W770P; G893P and G893P-G894A were inactive)\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/02/03
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:893-894
Feature(s) for interactor Bfluorescein isothiocyanate label:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BMolecular weight estimation by staining