Curation Details
Interaction ID: IM-22213-1

Unique identifier for interactor Auniprotkb:P36776
Unique identifier for interactor Buniprotkb:P36776
Alternative identifier for interactor Aintact:EBI-357448
intact:EBI-1054513
uniprotkb:D6W635
uniprotkb:E5KMH8
uniprotkb:P36777
uniprotkb:Q8N8K8
uniprotkb:Q9UQ95
uniprotkb:B3KPH8
uniprotkb:F5GZ27
intact:EBI-10964236
ensembl:ENSP00000353826.2
Alternative identifier for interactor Bintact:EBI-357448
intact:EBI-1054513
uniprotkb:D6W635
uniprotkb:E5KMH8
uniprotkb:P36777
uniprotkb:Q8N8K8
uniprotkb:Q9UQ95
uniprotkb:B3KPH8
uniprotkb:F5GZ27
intact:EBI-10964236
ensembl:ENSP00000353826.2
Aliases for Apsi-mi:lonm_human(display_long)
uniprotkb:LONHs(gene name synonym)
uniprotkb:PRSS15(gene name synonym)
uniprotkb:LONP1(gene name)
psi-mi:LONP1(display_short)
uniprotkb:Lon protease-like protein(gene name synonym)
uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)
uniprotkb:Serine protease 15(gene name synonym)
Aliases for Bpsi-mi:lonm_human(display_long)
uniprotkb:LONHs(gene name synonym)
uniprotkb:PRSS15(gene name synonym)
uniprotkb:LONP1(gene name)
psi-mi:LONP1(display_short)
uniprotkb:Lon protease-like protein(gene name synonym)
uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)
uniprotkb:Serine protease 15(gene name synonym)
Interaction detection methodspsi-mi:"MI:0030"(cross-linking study)
First authorAmbro et al. (2014)
Identifier of the publicationpubmed:24520911
imex:IM-22213
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9107219
imex:IM-22213-1
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:sf13
comment:"\"All mutants showed the same pattern of oligomerization as wild-type hLon by both gel-filtration and glutaraldehyde cross-linking (supplementary Figure S13). These residues, therefore, do not appear to be important for proper oligomerization. Correct oligomerization seems to be important for the proper functioning of Lon’s various activities, so verification that all mutants have the same oligomeric form as the wild-type allows us to directly compare their various activities and to look for the source of their differences only in their local effects\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/02/03
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?
Feature(s) for interactor Bhis tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by coomasie staining
Participant identification method for interactor BMolecular weight estimation by coomasie staining