| Unique identifier for interactor A | uniprotkb:P63165 |
| Unique identifier for interactor B | uniprotkb:P45481 |
| Alternative identifier for interactor A | intact:EBI-80140 uniprotkb:B2R4I5 uniprotkb:A8MUS8 uniprotkb:P55856 uniprotkb:Q6FGG0 uniprotkb:Q6NZ62 uniprotkb:Q93068 intact:EBI-28970052 ensembl:ENSP00000376076.1 ensembl:ENSP00000376077.2 |
| Alternative identifier for interactor B | intact:EBI-296306 uniprotkb:E9QPH4 |
| Aliases for A | psi-mi:sumo1_human(display_long) uniprotkb:SUMO1(gene name) psi-mi:SUMO1(display_short) uniprotkb:Sentrin(gene name synonym) uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym) uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) uniprotkb:Ubiquitin-like protein UBL1(gene name synonym) uniprotkb:GAP-modifying protein 1(gene name synonym) uniprotkb:SMT3 homolog 3(gene name synonym) uniprotkb:SMT3C(gene name synonym) uniprotkb:SMT3H3(gene name synonym) uniprotkb:UBL1(gene name synonym) uniprotkb:OK/SW-cl.43(orf name) |
| Aliases for B | psi-mi:cbp_mouse(display_long) uniprotkb:Crebbp(gene name) psi-mi:Crebbp(display_short) uniprotkb:Cbp(gene name synonym) uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Hsieh et al. (2013) |
| Identifier of the publication | pubmed:23395904 imex:IM-22208 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9210386 imex:IM-22208-4 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f1c f3f comment:"\"As expected, we found that sumoylation levels of the Elk-1 E3A mutant, in which three acidic residues located C-terminal to the core c-K-X-E/D motif were replaced with Ala (Figure 1A), were insensitive to HDAC inhibitor treatment (Figure 1B, lanes 4 and 5). Notably, the acidic residue mutant E3A reduced the potential of Elk-1 for sumoylation (lanes 4 versus 2), consistent with a previous report (Yang et al., 2006)\"" comment:"\"n addition, sumoylation levels of Elk-1 acidic residue mutant E3A were not significantly altered by SRT1720 or sirtinol treatment, compared to WT (Supplementary Figure S4C and D, lanes 2–5). These results suggest that SIRT1 modulates NDSM substrate Elk-1 sumoy- lation, likely via Ubc9 K65 acetylation.\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2014/02/17 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | green fluorescent protein tag:?-? |
| Feature(s) for interactor B | binding-associated region:900-1100 mutation decreasing interaction:1062-1065 ha tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |