| Unique identifier for interactor A | uniprotkb:Q9UER7 |
| Unique identifier for interactor B | uniprotkb:P63165 |
| Alternative identifier for interactor A | intact:EBI-77321 uniprotkb:O14747 uniprotkb:O15141 uniprotkb:O15208 uniprotkb:Q9BWI3 ensembl:ENSP00000266000.6 ensembl:ENSP00000363668.5 ensembl:ENSP00000372539.4 ensembl:ENSP00000372681.4 ensembl:ENSP00000382014.3 ensembl:ENSP00000382281.3 ensembl:ENSP00000394108.2 ensembl:ENSP00000404376.2 ensembl:ENSP00000404623.1 ensembl:ENSP00000410772.2 uniprotkb:B4E1I3 uniprotkb:F5H082 uniprotkb:Q5STK9 uniprotkb:F5ANJ6 uniprotkb:F5ANJ7 |
| Alternative identifier for interactor B | intact:EBI-80140 uniprotkb:P55856 uniprotkb:Q6FGG0 uniprotkb:Q6NZ62 uniprotkb:Q93068 intact:EBI-28970052 uniprotkb:B2R4I5 uniprotkb:A8MUS8 ensembl:ENSP00000376076.1 ensembl:ENSP00000376077.2 |
| Aliases for A | psi-mi:daxx_human(display_long) uniprotkb:DAXX(gene name) psi-mi:DAXX(display_short) uniprotkb:BING2(gene name synonym) uniprotkb:DAP6(gene name synonym) uniprotkb:Daxx(gene name synonym) uniprotkb:Fas death domain-associated protein(gene name synonym) uniprotkb:ETS1-associated protein 1(gene name synonym) |
| Aliases for B | psi-mi:sumo1_human(display_long) uniprotkb:SUMO1(gene name) psi-mi:SUMO1(display_short) uniprotkb:Sentrin(gene name synonym) uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym) uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) uniprotkb:Ubiquitin-like protein UBL1(gene name synonym) uniprotkb:GAP-modifying protein 1(gene name synonym) uniprotkb:SMT3 homolog 3(gene name synonym) uniprotkb:SMT3C(gene name synonym) uniprotkb:SMT3H3(gene name synonym) uniprotkb:UBL1(gene name synonym) uniprotkb:OK/SW-cl.43(orf name) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Hsieh et al. (2013) |
| Identifier of the publication | pubmed:23395904 imex:IM-22208 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9210372 imex:IM-22208-3 |
| Confidence score | intact-miscore:0.78 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f1d f3g comment:"\"As expected, we found that sumoylation levels of the Elk-1 E3A mutant, in which three acidic residues located C-terminal to the core c-K-X-E/D motif were replaced with Ala (Figure 1A), were insensitive to HDAC inhibitor treatment (Figure 1B, lanes 4 and 5). Notably, the acidic residue mutant E3A reduced the potential of Elk-1 for sumoylation (lanes 4 versus 2), consistent with a previous report (Yang et al., 2006)\"" comment:"\"n addition, sumoylation levels of Elk-1 acidic residue mutant E3A were not significantly altered by SRT1720 or sirtinol treatment, compared to WT (Supplementary Figure S4C and D, lanes 2–5). These results suggest that SIRT1 modulates NDSM substrate Elk-1 sumoy- lation, likely via Ubc9 K65 acetylation.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2014/02/17 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? |
| Feature(s) for interactor B | green fluorescent protein tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |