| Unique identifier for interactor A | uniprotkb:P17655 |
| Unique identifier for interactor B | uniprotkb:P63165 |
| Alternative identifier for interactor A | intact:EBI-1028956 uniprotkb:A6NDG7 uniprotkb:B7ZA96 uniprotkb:E7ES58 ensembl:ENSP00000295006.5 uniprotkb:Q16738 uniprotkb:Q6PJT3 uniprotkb:Q8WU26 uniprotkb:Q9HBB1 |
| Alternative identifier for interactor B | intact:EBI-80140 uniprotkb:B2R4I5 uniprotkb:A8MUS8 uniprotkb:P55856 uniprotkb:Q6FGG0 uniprotkb:Q6NZ62 uniprotkb:Q93068 intact:EBI-28970052 ensembl:ENSP00000376076.1 ensembl:ENSP00000376077.2 |
| Aliases for A | psi-mi:can2_human(display_long) uniprotkb:CAPN2(gene name) psi-mi:CAPN2(display_short) uniprotkb:CANPL2(gene name synonym) uniprotkb:Calpain-2 large subunit(gene name synonym) uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym) uniprotkb:Calpain M-type(gene name synonym) uniprotkb:Millimolar-calpain(gene name synonym) uniprotkb:Calpain large polypeptide L2(gene name synonym) |
| Aliases for B | psi-mi:sumo1_human(display_long) uniprotkb:SUMO1(gene name) psi-mi:SUMO1(display_short) uniprotkb:Sentrin(gene name synonym) uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym) uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) uniprotkb:Ubiquitin-like protein UBL1(gene name synonym) uniprotkb:GAP-modifying protein 1(gene name synonym) uniprotkb:SMT3 homolog 3(gene name synonym) uniprotkb:SMT3C(gene name synonym) uniprotkb:SMT3H3(gene name synonym) uniprotkb:UBL1(gene name synonym) uniprotkb:OK/SW-cl.43(orf name) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Hsieh et al. (2013) |
| Identifier of the publication | pubmed:23395904 imex:IM-22208 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9212484 imex:IM-22208-11 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:sf1 sf3c comment:"\"These results suggest an important role for negatively charged amino-acid residues, within the NDSM substrate, in responding to HDAC inhibitor treatment. Our data also showed that the sumoylation levels of two other NDSM substrates, CBP and calpain-2, were sensitive to HDAC inhibitor treatment (Figure 1C; Supplementary Figure S1, lanes 2 and 3), further supporting the specificity of NDSM substrate sumoylation modulated by HDAC inhibitors. Likewise, mutation of the negatively charged amino-acid residues of CBP and calpain-2 to Ala also attenuated the effect of HDAC inhibitor on sumoylation of both factors (Figure 1C; Supplementary Figure S1, lanes 4 and 5).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2014/02/17 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? mutation decreasing interaction:395-395,396-396,397-397,398-398 |
| Feature(s) for interactor B | green fluorescent protein tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |