Curation Details
Interaction ID: IM-22206-26

Unique identifier for interactor Auniprotkb:Q70E73
Unique identifier for interactor Buniprotkb:Q6PFA2
Alternative identifier for interactor Aintact:EBI-3940924
uniprotkb:Q9C0I2
uniprotkb:Q96Q37
ensembl:ENSP00000316543.5
Alternative identifier for interactor Bintact:EBI-1634219
ensembl:ENSMUSP00000103478.4
ensembl:ENSMUSP00000127344.2
Aliases for Apsi-mi:raph1_human(display_long)
uniprotkb:RAPH1(gene name)
psi-mi:RAPH1(display_short)
uniprotkb:ALS2CR18(gene name synonym)
uniprotkb:ALS2CR9(gene name synonym)
uniprotkb:KIAA1681(gene name synonym)
uniprotkb:LPD(gene name synonym)
uniprotkb:PREL2(gene name synonym)
uniprotkb:RMO1(gene name synonym)
uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)
uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)
uniprotkb:Lamellipodin(gene name synonym)
uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)
uniprotkb:Protein RMO1(gene name synonym)
Aliases for Bpsi-mi:q6pfa2_mouse(display_long)
uniprotkb:Clta(gene name)
psi-mi:Clta(display_short)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorVehlow et al. (2013)
Identifier of the publicationimex:IM-22206
pubmed:24076656
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9160566
imex:IM-22206-26
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4g f4i f4j
comment:"\"On average 28% of clathrin spots colocalized with Lpd, whereas 53% of Lpd‐positive spots colocalized with clathrin (Figure 4G), suggesting that Lpd is dynamically recruited to CCPs.\""
comment:"\"To analyse whether Lpd dynamically localizes to CCPs, we quantified Lpd recruitment during CCP scission in TIRFM movies. This analysis revealed that Lpd‐GFP colocalized with 57% of mRFP‐Clc labelled CCPs shortly before their scission (Figure 4I and J; Supplementary Movie S3).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2014/02/06
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:?-?
Feature(s) for interactor Bred fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by fluorescence
Participant identification method for interactor BTag visualisation by fluorescence