Curation Details
Interaction ID: IM-22198-6

Unique identifier for interactor Auniprotkb:O94829
Unique identifier for interactor Buniprotkb:P47813
Alternative identifier for interactor Aintact:EBI-747310
uniprotkb:D3DPY4
ensembl:ENSP00000361418.3
uniprotkb:Q7LC04
uniprotkb:Q96HS3
uniprotkb:Q9H8N3
uniprotkb:Q9UFR1
uniprotkb:Q5T4X3
Alternative identifier for interactor Bintact:EBI-1045377
uniprotkb:B2R5U5
ensembl:ENSP00000368927.5
uniprotkb:Q0VGC2
uniprotkb:Q5JPS5
uniprotkb:Q5JPS6
Aliases for Apsi-mi:ipo13_human(display_long)
uniprotkb:Ran-binding protein 13(gene name synonym)
uniprotkb:Karyopherin-13(gene name synonym)
uniprotkb:IPO13(gene name)
psi-mi:IPO13(display_short)
uniprotkb:KIAA0724(gene name synonym)
uniprotkb:RANBP13(gene name synonym)
Aliases for Bpsi-mi:if1ax_human(display_long)
uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)
uniprotkb:EIF1AX(gene name)
psi-mi:EIF1AX(display_short)
uniprotkb:EIF1A(gene name synonym)
uniprotkb:EIF4C(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorGrünwald et al. (2013)
Identifier of the publicationpubmed:23435562
imex:IM-22198
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9207938
imex:IM-22198-6
Confidence scoreintact-miscore:0.75
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2c
comment:"\"Consistent with the structural analysis, reverse charge mutations of Asp369I, Asp370I, Glu436I and Asp481I to arginine in BS1 or of Arg938I to glutamate in BS2 resulted in reduction or loss of binding to eIF1A in pull-down assays (Figure 2C; Supplementary Figure 1).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/02/17
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:436-436
glutathione s tranferase tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by coomasie staining
Participant identification method for interactor BMolecular weight estimation by coomasie staining