| Unique identifier for interactor A | uniprotkb:O94829 |
| Unique identifier for interactor B | uniprotkb:P62826 |
| Alternative identifier for interactor A | intact:EBI-747310 uniprotkb:D3DPY4 ensembl:ENSP00000361418.3 uniprotkb:Q7LC04 uniprotkb:Q96HS3 uniprotkb:Q9H8N3 uniprotkb:Q9UFR1 uniprotkb:Q5T4X3 |
| Alternative identifier for interactor B | intact:EBI-286642 uniprotkb:A8K3Z8 ensembl:ENSP00000446215.1 ensembl:ENSP00000376176.2 uniprotkb:P17080 uniprotkb:P28746 uniprotkb:P28747 uniprotkb:Q6IPB2 uniprotkb:Q86V08 uniprotkb:Q8NI90 uniprotkb:Q9CZA2 uniprotkb:Q9CSP3 uniprotkb:Q9CWI7 uniprotkb:Q9UDJ5 uniprotkb:Q9UEU9 |
| Aliases for A | psi-mi:ipo13_human(display_long) uniprotkb:Ran-binding protein 13(gene name synonym) uniprotkb:Karyopherin-13(gene name synonym) uniprotkb:IPO13(gene name) psi-mi:IPO13(display_short) uniprotkb:KIAA0724(gene name synonym) uniprotkb:RANBP13(gene name synonym) |
| Aliases for B | psi-mi:ran_human(display_long) uniprotkb:GTPase Ran(gene name synonym) uniprotkb:Ras-related nuclear protein(gene name synonym) uniprotkb:Ras-like protein TC4(gene name synonym) uniprotkb:Androgen receptor-associated protein 24(gene name synonym) uniprotkb:RAN(gene name) psi-mi:RAN(display_short) uniprotkb:ARA24(gene name synonym) uniprotkb:OK/SW-cl.81(orf name) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Grünwald et al. (2013) |
| Identifier of the publication | pubmed:23435562 imex:IM-22198 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9208167 imex:IM-22198-18 |
| Confidence score | intact-miscore:0.73 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f5a comment:"\"Consistent with the structural analysis, reverse charge mutations of Asp369I, Asp370I, Glu436I and Asp481I to arginine in BS1 or of Arg938I to glutamate in BS2 resulted in reduction or loss of binding to eIF1A in pull-down assays (Figure 2C; Supplementary Figure 1).\"" comment:"\"Notably, an Imp13 mutant unable to bind to Mago-Y14 (Lys803Glu/Arg803GluI) is also less efficient in exporting eIF1A in vivo (Figure 4I and K), reflecting a reduction in binding to eIF1A in vitro (Figure 5A).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/02/17 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation decreasing interaction:802-803 glutathione s tranferase tag:?-? |
| Feature(s) for interactor B | binding-associated region:1-180 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Molecular weight estimation by coomasie staining |
| Participant identification method for interactor B | Molecular weight estimation by coomasie staining |