Curation Details
Interaction ID: IM-22099-8

Unique identifier for interactor Auniprotkb:Q15075
Unique identifier for interactor Buniprotkb:Q9H6Y7
Alternative identifier for interactor Aintact:EBI-298113
uniprotkb:Q14221
ensembl:ENSP00000317955.8
Alternative identifier for interactor Bintact:EBI-1055214
uniprotkb:Q6XYE0
uniprotkb:Q8NDC1
uniprotkb:Q9Y3V1
uniprotkb:I3L0L6
uniprotkb:D3DTK8
ensembl:ENSP00000262482.6
ensembl:ENSP00000458794.1
ensembl:ENSP00000459324.1
ensembl:ENSP00000460190.1
Aliases for Apsi-mi:eea1_human(display_long)
uniprotkb:EEA1(gene name)
psi-mi:EEA1(display_short)
uniprotkb:ZFYVE2(gene name synonym)
uniprotkb:Endosome-associated protein p162(gene name synonym)
uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)
Aliases for Bpsi-mi:rn167_human(display_long)
uniprotkb:RING finger protein 167(gene name synonym)
uniprotkb:RING105(gene name synonym)
uniprotkb:RNF167(gene name)
psi-mi:RNF167(display_short)
uniprotkb:LP2254(orf name)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorYamazaki et al. (2013)
Identifier of the publicationimex:IM-22099
pubmed:23353890
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9101742
imex:IM-22099-8
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6a
comment:"\"Consistent with this we found that expression of human RNF167 also led to the accumulation of giant endosomes that were positive for EEA1, FK2 and VAMP3, with a concomitant loss of Rab11‐positive recycling endosomes (Figure 6A and B).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2014/01/13
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bgreen fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BTag visualisation by fluorescence