Curation Details
Interaction ID: IM-22099-6

Unique identifier for interactor Auniprotkb:Q15836
Unique identifier for interactor Buniprotkb:Q9VI20
Alternative identifier for interactor Aintact:EBI-722343
uniprotkb:Q9BRV4
ensembl:ENSP00000054666.6
Alternative identifier for interactor Bintact:EBI-135970
uniprotkb:Q8T089
Aliases for Apsi-mi:vamp3_human(display_long)
uniprotkb:Synaptobrevin-3(gene name synonym)
uniprotkb:Cellubrevin(gene name synonym)
uniprotkb:VAMP3(gene name)
psi-mi:VAMP3(display_short)
uniprotkb:SYB3(gene name synonym)
Aliases for Bpsi-mi:gzl_drome(display_long)
uniprotkb:gzl(gene name)
psi-mi:gzl(display_short)
uniprotkb:CG10277(orf name)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorYamazaki et al. (2013)
Identifier of the publicationimex:IM-22099
pubmed:23353890
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:7227(drome)
taxid:7227("Drosophila melanogaster (Fruit fly)")
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9099981
imex:IM-22099-6
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f5c
comment:"\"In order to confirm whether VAMP3 is a potential target of Godzilla, we investigated VAMP3 localization in Godzilla‐transfected HEK293 cells. VAMP3 is known to localize on both early and recycling endosomes and is involved in endocytic recycling (McMahon et al, 1993; Galli et al, 1994). In both control and ligase‐dead Godzilla‐transfected cells, VAMP3 displays a similar intracellular distribution, partially overlapping with ligase‐dead Godzilla; suggesting an early and recycling endosome distribution (Figure 5C). In contrast, in cells expressing wild‐type Godzilla VAMP3 is found on enlarged endosomes, where it colocalizes with Godzilla (Figure 5C).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2014/01/13
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:?-?
Feature(s) for interactor Bgreen fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by fluorescence
Participant identification method for interactor BTag visualisation by fluorescence