| Unique identifier for interactor A | uniprotkb:O14925 |
| Unique identifier for interactor B | uniprotkb:Q9BXM7 |
| Alternative identifier for interactor A | intact:EBI-1047996 uniprotkb:Q53FF8 uniprotkb:Q6P5S5 uniprotkb:Q5T1E6 ensembl:ENSP00000464522.3 |
| Alternative identifier for interactor B | intact:EBI-2846068 uniprotkb:Q8N6T9 uniprotkb:Q8NBU3 uniprotkb:Q96DE4 ensembl:ENSP00000364204.3 |
| Aliases for A | psi-mi:tim23_human(display_long) uniprotkb:TIMM23(gene name) psi-mi:TIMM23(display_short) uniprotkb:TIM23(gene name synonym) |
| Aliases for B | psi-mi:pink1_human(display_long) uniprotkb:PINK1(gene name) psi-mi:PINK1(display_short) uniprotkb:BRPK(gene name synonym) uniprotkb:PTEN-induced putative kinase protein 1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0027"(cosedimentation) |
| First author | Fedorowicz et al. (2014) |
| Identifier of the publication | imex:IM-22096 pubmed:24357652 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9107512 imex:IM-22096-1 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f1a comment:"\"Here, we transiently transfected HeLa cells with HA‐tagged human PINK1 and treated them with either MG132, valinomycin or both for 8 h. Incubation with MG132 was associated with a marked increase in PINK152, not only in the crude mitochondrial fraction but also in the cytosolic fraction (Fig 1A), confirming that PINK152 is present in both cellular compartments [12], [13], [14], [15], [16]. Conversely, incubation with valinomycin was associated with a decrease in PINK152 in both subcellular fractions while there was an increase in PINK163 in the mitochondrial fractions (Fig 1A). Finally, the combination of valinomycin and MG132 decreased the content of PINK152 in both subcellular fractions compared to MG132 alone (Fig 1A).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/01/31 |
| Update date | 2025/03/31 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | ha tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |