| Unique identifier for interactor A | uniprotkb:Q12929 |
| Unique identifier for interactor B | uniprotkb:Q9UQB8-4 |
| Alternative identifier for interactor A | intact:EBI-375576 uniprotkb:B4DX66 uniprotkb:A8K6W2 uniprotkb:A8KA66 ensembl:ENSP00000281172.5 ensembl:ENSP00000441867.1 ensembl:ENSP00000442388.1 ensembl:ENSP00000494689.1 ensembl:ENSP00000494842.1 ensembl:ENSP00000495722.1 ensembl:ENSP00000495824.1 ensembl:ENSP00000495956.1 ensembl:ENSP00000496406.1 ensembl:ENSP00000496516.1 uniprotkb:A6NMC3 uniprotkb:Q8N6J0 |
| Alternative identifier for interactor B | intact:EBI-6174091 ensembl:ENSP00000315685.7 |
| Aliases for A | psi-mi:eps8_human(display_long) uniprotkb:EPS8(gene name) psi-mi:EPS8(display_short) |
| Aliases for B | psi-mi:q9uqb8-4(display_long) uniprotkb:BAIAP2-alpha(isoform synonym) uniprotkb:BAIAP2(gene name) psi-mi:BAIAP2(display_short) uniprotkb:Fas ligand-associated factor 3(gene name synonym) uniprotkb:Insulin receptor substrate p53/p58(gene name synonym) uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Disanza et al. (2013) |
| Identifier of the publication | imex:IM-22092 pubmed:24076653 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9201991 imex:IM-22092-13 |
| Confidence score | intact-miscore:0.72 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"The ectopic expression of active CDC42, but not of a dominant‐negative mutant, significantly enhanced the amount of endogeneous IRSp53 co‐immunoprecipitating with VASP (Figure 3C). The CDC42‐dependent increase in the VASP:IRSp53 association was accompanied by a diminution of the EPS8:IRSp53 interaction (Figure 3C).\"" figure legend:f3c full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2014/02/04 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |