| Unique identifier for interactor A | uniprotkb:O00499 |
| Unique identifier for interactor B | uniprotkb:Q13496 |
| Alternative identifier for interactor A | intact:EBI-719094 uniprotkb:Q659B7 uniprotkb:O00545 uniprotkb:O00297 uniprotkb:O43867 uniprotkb:O60552 uniprotkb:O60553 uniprotkb:O60554 uniprotkb:O60555 uniprotkb:O75514 uniprotkb:O75515 uniprotkb:O75516 uniprotkb:O75517 uniprotkb:O75518 uniprotkb:Q92944 uniprotkb:Q99688 intact:EBI-1760307 intact:EBI-1965383 intact:EBI-28970933 ensembl:ENSP00000316779.5 intact:EBI-26518603 |
| Alternative identifier for interactor B | intact:EBI-2864109 uniprotkb:Q8NEL1 uniprotkb:A6NDB1 ensembl:ENSP00000359423.3 ensembl:ENSP00000508718.1 ensembl:ENSP00000509266.1 uniprotkb:B7Z491 uniprotkb:F2Z330 |
| Aliases for A | psi-mi:bin1_human(display_long) uniprotkb:Bridging integrator 1(gene name synonym) uniprotkb:Amphiphysin-like protein(gene name synonym) uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym) uniprotkb:BIN1(gene name) psi-mi:BIN1(display_short) uniprotkb:AMPHL(gene name synonym) uniprotkb:Amphiphysin II(gene name synonym) |
| Aliases for B | psi-mi:mtm1_human(display_long) uniprotkb:MTM1(gene name) psi-mi:MTM1(display_short) uniprotkb:CG2(gene name synonym) uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym) uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Royer et al. (2013) |
| Identifier of the publication | pubmed:23917616 imex:IM-22063 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9104825 imex:IM-22063-2 |
| Confidence score | intact-miscore:0.60 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f5a sf1 sf7 comment:"\"GFP-tagged BARþPI, BAR, SH3 and BIN1 FL co-immunoprecipitated with B10-MTM1 (Fig 1B). Similar results were obtained when the co-immunoprecipitation was performed in the reverse direction (supplementary Fig S1 online). Moreover, GST-tagged BIN1 full length, BAR and SH3, produced in bacteria, were able to pull down in vitro-translated B10-MTM1 (Fig 1C), suggesting that MTM1 interacts directly with BIN1.The stronger interaction observed after co-immunoprecipitation and pull-down with BAR and SH3 domains compared with BIN1 FL (Fig 1B,C; supplementary Fig S1 online) suggested MTM1 interaction depends on BIN1 conformation\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cv-1) taxid:9534(Monkey African Green kidney fibroblast) |
| Parameters of the interaction | - |
| Creation date | 2014/01/28 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation increasing interaction:573-573 green fluorescent protein tag:?-? |
| Feature(s) for interactor B | tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Predetermined participant |