Curation Details
Interaction ID: IM-22026-4

Unique identifier for interactor Auniprotkb:P01100
Unique identifier for interactor Buniprotkb:P35232
Alternative identifier for interactor Aintact:EBI-852851
uniprotkb:A8K4E2
uniprotkb:B4DQ65
ensembl:ENSP00000306245.4
uniprotkb:P18849
Alternative identifier for interactor Bintact:EBI-354213
ensembl:ENSP00000300408.3
ensembl:ENSP00000393320.3
ensembl:ENSP00000422182.3
ensembl:ENSP00000425035.2
ensembl:ENSP00000426433.3
ensembl:ENSP00000479488.1
ensembl:ENSP00000484113.1
uniprotkb:B4DY47
uniprotkb:Q4VBQ0
Aliases for Apsi-mi:fos_human(display_long)
uniprotkb:Cellular oncogene fos(gene name synonym)
uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)
uniprotkb:FOS(gene name)
psi-mi:FOS(display_short)
uniprotkb:G0S7(gene name synonym)
uniprotkb:Proto-oncogene c-Fos(gene name synonym)
uniprotkb:Transcription factor AP-1 subunit c-Fos(gene name synonym)
uniprotkb:Fos proto-oncogene, AP-1 transcription factor subunit(gene name synonym)
Aliases for Bpsi-mi:phb1_human(display_long)
uniprotkb:PHB1(gene name)
psi-mi:PHB1(display_short)
uniprotkb:PHB(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorSong et al. (2013)
Identifier of the publicationpubmed:24380853
imex:IM-22026
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9031429
imex:IM-22026-4
Confidence scoreintact-miscore:0.45
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3s f3t f3u f3v f3w f3x
comment:"\"The result of merged fluorescence revealed that PHB co-localized with c-Fos in the cytoplasm, especially near the nuclear membrane (Figure 3 S–U). After treatment with ESC-3, the green c-Fos fluorescence was greatly decreased in the cytoplasm and was primarily localized to the nucleus. The merged yellow fluorescence suggested that the co-localization of PHB with c-Fos decreased in the cytoplasm and increased 9 in the nucleus, indicating that the co-localization of PHB with c-Fos shifted from the cytoplasm to the nucleus (Figure 3 V–X).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-liver)
taxid:9606(Homo sapiens liver)
Parameters of the interaction-
Creation date2013/12/11
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining