Curation Details
Interaction ID: IM-22026-2

Unique identifier for interactor Auniprotkb:P35232
Unique identifier for interactor Buniprotkb:P04637
Alternative identifier for interactor Aintact:EBI-354213
uniprotkb:Q4VBQ0
uniprotkb:B4DY47
ensembl:ENSP00000300408.3
ensembl:ENSP00000393320.3
ensembl:ENSP00000422182.3
ensembl:ENSP00000425035.2
ensembl:ENSP00000426433.3
ensembl:ENSP00000479488.1
ensembl:ENSP00000484113.1
Alternative identifier for interactor Bintact:EBI-366083
uniprotkb:Q15086
uniprotkb:Q15087
uniprotkb:Q15088
uniprotkb:Q16535
uniprotkb:Q16807
uniprotkb:Q16808
uniprotkb:Q16809
uniprotkb:Q16810
uniprotkb:Q16811
uniprotkb:Q16848
uniprotkb:Q86UG1
uniprotkb:Q8J016
uniprotkb:Q99659
uniprotkb:Q9BTM4
uniprotkb:Q9HAQ8
uniprotkb:Q9NP68
uniprotkb:Q9NPJ2
uniprotkb:Q9NZD0
uniprotkb:Q9UBI2
uniprotkb:Q9UQ61
intact:EBI-28980681
ensembl:ENSP00000269305.4
ensembl:ENSP00000391478.2
ensembl:ENSP00000424104.2
ensembl:ENSP00000426252.2
uniprotkb:Q2XN98
uniprotkb:Q3LRW1
uniprotkb:Q3LRW2
uniprotkb:Q3LRW3
uniprotkb:Q3LRW4
uniprotkb:Q3LRW5
Aliases for Apsi-mi:phb1_human(display_long)
uniprotkb:PHB1(gene name)
psi-mi:PHB1(display_short)
uniprotkb:PHB(gene name synonym)
Aliases for Bpsi-mi:p53_human(display_long)
uniprotkb:TP53(gene name)
psi-mi:TP53(display_short)
uniprotkb:P53(gene name synonym)
uniprotkb:Tumor suppressor p53(gene name synonym)
uniprotkb:Phosphoprotein p53(gene name synonym)
uniprotkb:Antigen NY-CO-13(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorSong et al. (2013)
Identifier of the publicationpubmed:24380853
imex:IM-22026
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9031406
imex:IM-22026-2
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3g f3h f3i f3j f3k f3l
comment:"\"The yellow merged fluorescence indicated that PHB clearly co-localized with p53 in the nuclear membrane region (Figure 3 G–I). After ESC-3 treatment, the green color was enhanced and was scattered in the nucleus. The merged fluorescence suggested that the region of co-localization between PHB and p53 was clearly in the nucleus and was moderately decreased in the cytoplasm near the nuclear membrane (Figure 3 J–L).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-liver)
taxid:9606(Homo sapiens liver)
Parameters of the interaction-
Creation date2013/12/11
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining