Curation Details
Interaction ID: IM-22026-1

Unique identifier for interactor Auniprotkb:P55008
Unique identifier for interactor Buniprotkb:P35232
Alternative identifier for interactor Aintact:EBI-9031341
uniprotkb:A8K406
uniprotkb:O43904
uniprotkb:Q9UIV4
uniprotkb:Q9UKS9
ensembl:ENSP00000365227.3
ensembl:ENSP00000372966.4
ensembl:ENSP00000391720.2
ensembl:ENSP00000397842.2
ensembl:ENSP00000398013.2
ensembl:ENSP00000416061.2
Alternative identifier for interactor Bintact:EBI-354213
ensembl:ENSP00000300408.3
ensembl:ENSP00000393320.3
ensembl:ENSP00000422182.3
ensembl:ENSP00000425035.2
ensembl:ENSP00000426433.3
ensembl:ENSP00000479488.1
ensembl:ENSP00000484113.1
uniprotkb:B4DY47
uniprotkb:Q4VBQ0
Aliases for Apsi-mi:aif1_human(display_long)
uniprotkb:AIF1(gene name)
psi-mi:AIF1(display_short)
uniprotkb:G1(gene name synonym)
uniprotkb:IBA1(gene name synonym)
uniprotkb:Ionized calcium-binding adapter molecule 1(gene name synonym)
uniprotkb:Protein G1(gene name synonym)
Aliases for Bpsi-mi:phb1_human(display_long)
uniprotkb:PHB1(gene name)
psi-mi:PHB1(display_short)
uniprotkb:PHB(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorSong et al. (2013)
Identifier of the publicationpubmed:24380853
imex:IM-22026
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9031329
imex:IM-22026-1
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3a f3b f3c f3d f3e f3f
comment:"\"The results of merged fluorescence revealed that PHB co-localized with AIF near the nuclear membrane (Figure 3 A–C). After treatment, the green fluorescence of AIF was greatly enhanced and uniformly distributed in the nucleus. The merged fluorescence revealed that the co-localization of PHB with AIF was clearly present in the nucleus but not in the cytoplasm, suggesting that the co-localization between PHB and AIF disappeared from the cytoplasm adjacent to the nuclear membrane (Figure 3 D–F).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-liver)
taxid:9606(Homo sapiens liver)
Parameters of the interaction-
Creation date2013/12/11
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining