Curation Details
Interaction ID: IM-22015-3

Unique identifier for interactor Auniprotkb:Q05655
Unique identifier for interactor Buniprotkb:P24001-2
Alternative identifier for interactor Aintact:EBI-704279
uniprotkb:B0KZ81
ensembl:ENSP00000331602.3
ensembl:ENSP00000378217.2
ensembl:ENSP00000498400.1
ensembl:ENSP00000498623.1
ensembl:ENSP00000499558.1
uniprotkb:B2R834
uniprotkb:Q86XJ6
uniprotkb:Q15144
Alternative identifier for interactor Bintact:EBI-8800907
ensembl:ENSP00000324742.5
ensembl:ENSP00000405063.3
ensembl:ENSP00000411958.3
ensembl:ENSP00000432218.3
ensembl:ENSP00000432850.2
ensembl:ENSP00000432917.2
ensembl:ENSP00000436929.2
ensembl:ENSP00000437020.1
ensembl:ENSP00000448683.1
ensembl:ENSP00000450364.1
Aliases for Apsi-mi:kpcd_human(display_long)
uniprotkb:nPKC-delta(gene name synonym)
uniprotkb:PRKCD(gene name)
psi-mi:PRKCD(display_short)
uniprotkb:Tyrosine-protein kinase PRKCD(gene name synonym)
uniprotkb:PKCD(gene name synonym)
Aliases for Bpsi-mi:p24001-2(display_long)
uniprotkb:Beta(isoform synonym)
uniprotkb:IL32(gene name)
psi-mi:IL32(display_short)
uniprotkb:NK4(gene name synonym)
uniprotkb:TAIF(gene name synonym)
uniprotkb:Natural killer cells protein 4(gene name synonym)
uniprotkb:Tumor necrosis factor alpha-inducing factor(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorKang et al. (2013)
Identifier of the publicationpubmed:24396867
imex:IM-22015
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8800942
imex:IM-22015-3
Confidence scoreintact-miscore:0.73
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f5
comment:"\"We next verified the association profile of IL-32δ, IL-32β, and PKCδ by immunofluorescence staining in A549 cells. Both IL-32β and PKCδ were distributed in the cytosol in normal condition. However, they co-localized around the nucleus upon PMA treatment. Rottlerin disrupted their co-localization. As consistent with the immunoprecipitation data, IL-32δ induced the dissociation of IL-32β from PKCδ (Fig. 5). These data confirm the inhibitory effect of IL-32δ on IL-32β function.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2013/10/17
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor Bmyc tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining