| Unique identifier for interactor A | uniprotkb:P02647 |
| Unique identifier for interactor B | uniprotkb:P02647 |
| Alternative identifier for interactor A | intact:EBI-701692 uniprotkb:Q6LDN9 uniprotkb:Q6Q785 uniprotkb:A8K866 uniprotkb:Q9UCS8 uniprotkb:Q9UCT8 ensembl:ENSP00000236850.3 ensembl:ENSP00000352471.2 ensembl:ENSP00000364469.1 ensembl:ENSP00000364472.1 |
| Alternative identifier for interactor B | intact:EBI-701692 uniprotkb:Q6LDN9 uniprotkb:Q6Q785 uniprotkb:A8K866 uniprotkb:Q9UCS8 uniprotkb:Q9UCT8 ensembl:ENSP00000236850.3 ensembl:ENSP00000352471.2 ensembl:ENSP00000364469.1 ensembl:ENSP00000364472.1 |
| Aliases for A | psi-mi:apoa1_human(display_long) uniprotkb:APOA1(gene name) psi-mi:APOA1(display_short) uniprotkb:Apolipoprotein A1(gene name synonym) |
| Aliases for B | psi-mi:apoa1_human(display_long) uniprotkb:APOA1(gene name) psi-mi:APOA1(display_short) uniprotkb:Apolipoprotein A1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0051"(fluorescence technology) |
| First author | Adachi et al. (2013) |
| Identifier of the publication | pubmed:24316228 imex:IM-21817 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8874871 imex:IM-21817-6 |
| Confidence score | intact-miscore:0.97 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f1a f1c f3 f5a f5b sf4 sf5 comment:We first investigated the fibril-forming propensity of apoA-I 1-43, 44-65, and 66-83 peptides by monitoring the increase in ThT fluorescence, which is highly characteristic of amyloid fibril structure.We also performed ANS binding studies to the apoA-I peptides to examine the aggregated state over incubation time because this dye binds to the fibrillar or prefibrillar aggregate states of proteins curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2013/11/26 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation disrupting interaction:18-18 binding-associated region:1-43 |
| Feature(s) for interactor B | binding-associated region:1-43 mutation disrupting interaction:18-18 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |