| Unique identifier for interactor A | uniprotkb:Q8N944 |
| Unique identifier for interactor B | uniprotkb:P25054 |
| Alternative identifier for interactor A | intact:EBI-8869590 uniprotkb:B7ZLH6 ensembl:ENSP00000314914.4 ensembl:ENSP00000389242.2 ensembl:ENSP00000410421.2 |
| Alternative identifier for interactor B | intact:EBI-727707 uniprotkb:D3DT03 uniprotkb:B7Z2B6 ensembl:ENSP00000257430.4 ensembl:ENSP00000423828.3 ensembl:ENSP00000426541.2 ensembl:ENSP00000427089.2 uniprotkb:Q15162 uniprotkb:Q15163 uniprotkb:Q93042 |
| Aliases for A | psi-mi:amer3_human(display_long) uniprotkb:AMER3(gene name) psi-mi:AMER3(display_short) uniprotkb:FAM123C(gene name synonym) uniprotkb:Protein FAM123C(gene name synonym) |
| Aliases for B | psi-mi:apc_human(display_long) uniprotkb:APC(gene name) psi-mi:APC(display_short) uniprotkb:DP2.5(gene name synonym) uniprotkb:Deleted in polyposis 2.5(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0018"(two hybrid) |
| First author | Brauburger et al. (2013) |
| Identifier of the publication | pubmed:24251807 imex:IM-21815 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8870355 imex:IM-21815-14 |
| Confidence score | intact-miscore:0.63 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:sf3 comment:"\"Protein fragments containing either region A1 or A2 fused to a LexA DNA binding domain interacted with the VP16-fused armadillo repeats in yeast two-hybrid assays, indicating direct binding (Fig. S3). To narrow down the interaction sites, mutations of A1 and A2 were generated by deleting the highly conserved amino acid stretches within these regions (Fig. S3A). Mutated protein fragments with deletions A1 and A2 2 no longer bound the armadillo repeats of APC in yeast two-hybrid assays, whereas the deletion A2 1 had no effect on the interaction (Fig. S3B).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| Parameters of the interaction | - |
| Creation date | 2013/11/20 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | fusion protein:?-? binding-associated region:243-251 |
| Feature(s) for interactor B | fusion protein:?-? binding-associated region:308-789 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |