| Unique identifier for interactor A | uniprotkb:Q8WYA6 |
| Unique identifier for interactor B | uniprotkb:Q99459 |
| Alternative identifier for interactor A | intact:EBI-748128 uniprotkb:Q0VAL9 uniprotkb:Q53HI8 uniprotkb:Q5JWZ2 uniprotkb:Q5JWZ3 uniprotkb:Q5JWZ7 uniprotkb:Q5JWZ8 uniprotkb:Q8N454 uniprotkb:Q8NCL2 uniprotkb:Q8TBD6 uniprotkb:Q96KD2 uniprotkb:Q9H7A5 uniprotkb:Q9NQF9 uniprotkb:Q9NTX0 uniprotkb:B4DE16 uniprotkb:Q0VAM0 uniprotkb:Q9Y3M7 ensembl:ENSP00000355050.6 intact:EBI-11161095 |
| Alternative identifier for interactor B | intact:EBI-374880 uniprotkb:Q76N46 uniprotkb:Q99974 ensembl:ENSP00000360532.3 |
| Aliases for A | psi-mi:ctbl1_human(display_long) uniprotkb:Nuclear-associated protein(gene name synonym) uniprotkb:Testis development protein NYD-SP19(gene name synonym) uniprotkb:PP8304(orf name) uniprotkb:CTNNBL1(gene name) psi-mi:CTNNBL1(display_short) uniprotkb:C20orf33(gene name synonym) |
| Aliases for B | psi-mi:cdc5l_human(display_long) uniprotkb:CDC5L(gene name) psi-mi:CDC5L(display_short) uniprotkb:Pombe cdc5-related protein(gene name synonym) uniprotkb:KIAA0432(gene name synonym) uniprotkb:PCDC5RP(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0065"(isothermal titration calorimetry) |
| First author | Ganesh et al. (2013) |
| Identifier of the publication | pubmed:24269683 imex:IM-21761 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8845269 imex:IM-21761-1 |
| Confidence score | intact-miscore:0.81 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f4b sf5 comment:"\"Multiple mutants of CTNNBL1 were also generated that carried amino acid substitutions in the putative NLS recognition groove (Figure 4A). Strikingly, all mutants retained the ability to interact with the CDC5L NLS3 as judged by a pulldown assay (Figure 4C). Indeed, not only was NLS binding retained by these mutants, but the affinity of binding to the CDC5L NLS3 (as well as to the Prp31 NLS) peptide, as monitored by ITC, was little affected by these amino acid changes; the small differences in binding affinity, such as the deletion mutant K1, might reflect a minor influence on the stability of the protein (Supplementary Figure 5).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kd:4.0x10^-6(molar) |
| Creation date | 2013/11/07 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:77-563 |
| Feature(s) for interactor B | binding-associated region:200-206 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |