Curation Details
Interaction ID: IM-21759-1

Unique identifier for interactor Auniprotkb:P01275
Unique identifier for interactor Buniprotkb:P01308
Alternative identifier for interactor Aintact:EBI-7629173
ensembl:ENSP00000364647.3
ensembl:ENSP00000387662.2
uniprotkb:A6NN65
intact:MINT-8090511
uniprotkb:Q53TP6
Alternative identifier for interactor Bintact:EBI-7090529
ensembl:ENSP00000250971.3
ensembl:ENSP00000370731.5
ensembl:ENSP00000380432.1
uniprotkb:Q5EEX2
intact:MINT-106847
Aliases for Apsi-mi:gluc_human(display_long)
uniprotkb:GCG(gene name)
psi-mi:GCG(display_short)
Aliases for Bpsi-mi:ins_human(display_long)
uniprotkb:INS(gene name)
psi-mi:INS(display_short)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorRütti et al. (2013)
Identifier of the publicationpubmed:24239544
imex:IM-21759
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8841462
imex:IM-21759-1
Confidence scoreintact-miscore:0.27
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1b
comment:"\"we observed in dispersed human islet cells co-stained for TBC1D1 (red), insulin (green) and glucagon (cyan) that TBC1D1 co-localizes with both glucagon and insulin (Fig. 1B). These immunofluorescence results confirm that TBC1D1 is expressed at the protein level in both these human islets cell types.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2013/11/04
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining