Curation Details
Interaction ID: IM-21716-1

Unique identifier for interactor Auniprotkb:Q8NC51
Unique identifier for interactor Buniprotkb:P09651
Alternative identifier for interactor Aintact:EBI-523558
uniprotkb:Q8WUH0
uniprotkb:Q96SE2
uniprotkb:Q9BTY3
uniprotkb:Q9BUM4
uniprotkb:Q9Y367
uniprotkb:Q9Y4S3
uniprotkb:Q5VU19
intact:EBI-1058614
uniprotkb:Q5VU20
uniprotkb:Q5VU22
ensembl:ENSP00000360034.2
Alternative identifier for interactor Bintact:EBI-352662
uniprotkb:Q3MIB7
uniprotkb:Q6PJZ7
uniprotkb:A8K4Z8
intact:EBI-2556572
ensembl:ENSP00000341826.7
ensembl:ENSP00000503610.1
intact:EBI-21353669
Aliases for Apsi-mi:serb1_human(display_long)
uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)
uniprotkb:SERBP1(gene name)
psi-mi:SERBP1(display_short)
uniprotkb:PAIRBP1(gene name synonym)
uniprotkb:Plasminogen activator inhibitor 1 RNA-binding protein(gene name synonym)
uniprotkb:CGI-55(orf name)
Aliases for Bpsi-mi:roa1_human(display_long)
uniprotkb:HNRNPA1(gene name)
psi-mi:HNRNPA1(display_short)
uniprotkb:HNRPA1(gene name synonym)
uniprotkb:Helix-destabilizing protein(gene name synonym)
uniprotkb:Single-strand RNA-binding protein(gene name synonym)
uniprotkb:hnRNP core protein A1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorYu-Jen et al. (2013)
Identifier of the publicationpubmed:24205981
imex:IM-21716
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8844279
imex:IM-21716-1
Confidence scoreintact-miscore:0.55
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1a
comment:"\"We first showed that hnRNPA1 co-immunoprecipitated with FLAG-tagged SERBP1 (Fig. 1A). The interaction requires RNA because addition of RNase to the HeLa cell extract before the immunoprecipitation totally blocked the interaction. On the other hand, interaction of PRMT1 that can directly interact with SERBP1 [17] was not influenced by RNase treatment.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2013/11/06
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BWestern blot