Curation Details
Interaction ID: IM-21712-5

Unique identifier for interactor Auniprotkb:Q02750
Unique identifier for interactor Buniprotkb:Q9Y297
Alternative identifier for interactor Aintact:EBI-492564
ensembl:ENSP00000302486.5
Alternative identifier for interactor Bintact:EBI-307461
uniprotkb:Q9Y213
uniprotkb:B5MD49
uniprotkb:Q5W142
uniprotkb:Q5W141
ensembl:ENSP00000359206.3
Aliases for Apsi-mi:mp2k1_human(display_long)
uniprotkb:ERK activator kinase 1(gene name synonym)
uniprotkb:MAPK/ERK kinase 1(gene name synonym)
uniprotkb:MAP2K1(gene name)
psi-mi:MAP2K1(display_short)
uniprotkb:MEK1(gene name synonym)
uniprotkb:PRKMK1(gene name synonym)
Aliases for Bpsi-mi:fbw1a_human(display_long)
uniprotkb:BTRC(gene name)
psi-mi:BTRC(display_short)
uniprotkb:BTRCP(gene name synonym)
uniprotkb:FBW1A(gene name synonym)
uniprotkb:FBXW1A(gene name synonym)
uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)
uniprotkb:E3RSIkappaB(gene name synonym)
uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)
uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorLanlan et al. (2013)
Identifier of the publicationpubmed:24211253
imex:IM-21712
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8838419
imex:IM-21712-5
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f5g
comment:Interaction was confirmed in both HepG2 and Bel-7402 cells
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2013/10/30
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining