Curation Details
Interaction ID: IM-21711-2

Unique identifier for interactor Auniprotkb:P51610
Unique identifier for interactor Buniprotkb:Q92560
Alternative identifier for interactor Aintact:EBI-396176
intact:EBI-2832627
ensembl:ENSP00000309555.7
uniprotkb:Q6P4G5
intact:EBI-12037257
intact:EBI-14324845
intact:EBI-12980473
Alternative identifier for interactor Bintact:EBI-1791447
uniprotkb:Q6LEM0
uniprotkb:Q7Z5E8
uniprotkb:A8K993
intact:EBI-2558090
ensembl:ENSP00000417132.1
Aliases for Apsi-mi:hcfc1_human(display_long)
uniprotkb:HCFC1(gene name)
psi-mi:HCFC1(display_short)
uniprotkb:HCF1(gene name synonym)
uniprotkb:C1 factor(gene name synonym)
uniprotkb:VP16 accessory protein(gene name synonym)
uniprotkb:VCAF(gene name synonym)
uniprotkb:CFF(gene name synonym)
uniprotkb:HFC1(gene name synonym)
Aliases for Bpsi-mi:bap1_human(display_long)
uniprotkb:BAP1(gene name)
psi-mi:BAP1(display_short)
uniprotkb:KIAA0272(gene name synonym)
uniprotkb:hucep-6(orf name)
uniprotkb:BRCA1-associated protein 1(gene name synonym)
uniprotkb:Cerebral protein 6(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorZiad et al. (2013)
Identifier of the publicationpubmed:24211834
imex:IM-21711
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8829641
imex:IM-21711-2
Confidence scoreintact-miscore:0.74
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1b
comment:"\"To further assess whether the pS592-BAP1 antibody recognizes phosphorylated BAP1, we performed IPs of BAP1 and HCF-1 from endogenous HeLa SCEs (Fig 1B). Consistent with previous reports [5, 8], BAP1 only brings down a small fraction of HCF-1, while HCF-1 brings down a significant fraction of BAP1. In the absence of UV, there is no detectable pS592-signal in the IP inputs, yet after UV-treatment the pS592-BAP1 signal is induced and both BAP1 and HCF-1 coimmunoprecipitate pS592-BAP1.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2013/10/25
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bphosphorylated residue:592-592
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot