| Unique identifier for interactor A | uniprotkb:P16104 |
| Unique identifier for interactor B | uniprotkb:Q5VTR2 |
| Alternative identifier for interactor A | intact:EBI-494830 uniprotkb:Q4ZGJ7 uniprotkb:Q6IAS5 ensembl:ENSP00000364310.1 ensembl:ENSP00000434024.1 |
| Alternative identifier for interactor B | intact:EBI-2372238 uniprotkb:Q2TB34 uniprotkb:Q69YL5 uniprotkb:Q6P527 uniprotkb:Q8N3J4 uniprotkb:Q96JD3 uniprotkb:Q9H9Y7 uniprotkb:Q9HA51 uniprotkb:Q9NUR4 uniprotkb:Q9NWQ3 uniprotkb:Q9NX83 uniprotkb:A7MCT5 ensembl:ENSP00000373772.3 |
| Aliases for A | psi-mi:h2ax_human(display_long) uniprotkb:H2AX(gene name) psi-mi:H2AX(display_short) uniprotkb:H2AFX(gene name synonym) uniprotkb:Histone H2A.X(gene name synonym) |
| Aliases for B | psi-mi:bre1a_human(display_long) uniprotkb:RNF20(gene name) psi-mi:RNF20(display_short) uniprotkb:BRE1A(gene name synonym) uniprotkb:RING finger protein 20(gene name synonym) uniprotkb:RING-type E3 ubiquitin transferase BRE1A(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Arroyo et al. (2015) |
| Identifier of the publication | pubmed:25640309 imex:IM-21668 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10110800 imex:IM-21668-21 |
| Confidence score | intact-miscore:0.27 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f5c comment:"\"Hence, U2OS cells overexpressing our candidate genes were analyzed for IRIF formation and colocalization with γH2AX 1 h and 6 h post-irradiation (see Materials and Methods) [46]. We observed that both RNF20 and SNAI1 progressively re-localize into IRIF upon the induction of DNA damage by IR (Fig. 5c and d), providing further support that the recruitment of these proteins to IRIF may be indicative of a role in DSB repair or signaling.\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-u2os) taxid:9606(Homo sapiens U2OS osteosarcoma cell) |
| Parameters of the interaction | - |
| Creation date | 2013/12/18 |
| Update date | 2024/11/20 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunostaining |
| Participant identification method for interactor B | Immunostaining |