| Unique identifier for interactor A | uniprotkb:P54132 |
| Unique identifier for interactor B | uniprotkb:Q96RL1 |
| Alternative identifier for interactor A | intact:EBI-621372 ensembl:ENSP00000347232.3 ensembl:ENSP00000506117.1 uniprotkb:Q52M96 |
| Alternative identifier for interactor B | intact:EBI-725300 uniprotkb:A8MSA1 uniprotkb:B3KMZ1 uniprotkb:B4E3N2 ensembl:ENSP00000366434.4 ensembl:ENSP00000421926.1 intact:EBI-1263554 uniprotkb:Q5XKQ1 uniprotkb:Q7Z3W7 uniprotkb:Q8N5B9 uniprotkb:Q9BZR1 uniprotkb:Q9BZR5 uniprotkb:Q9UHX7 |
| Aliases for A | psi-mi:blm_human(display_long) uniprotkb:RecQ protein-like 3(gene name synonym) uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym) uniprotkb:BLM(gene name) psi-mi:BLM(display_short) uniprotkb:RECQ2(gene name synonym) uniprotkb:RECQL3(gene name synonym) uniprotkb:Bloom syndrome protein(gene name synonym) |
| Aliases for B | psi-mi:uimc1_human(display_long) uniprotkb:Retinoid X receptor-interacting protein 110(gene name synonym) uniprotkb:Receptor-associated protein 80(gene name synonym) uniprotkb:Ubiquitin interaction motif-containing protein 1(gene name synonym) uniprotkb:UIMC1(gene name) psi-mi:UIMC1(display_short) uniprotkb:RAP80(gene name synonym) uniprotkb:RXRIP110(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Tikoo et al. (2013) |
| Identifier of the publication | imex:IM-21664 pubmed:23708797 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8801376 imex:IM-21664-1 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f6a comment:"\"reciprocal co-immunoprecipitations were carried out using extracts derived from cells treated with and without HU. In keeping with the idea that RAP80 acts as a receptor for ubiquitylated BLM in response to DNA damage, we observed that BLM and RAP80 co-precipitated together in asynchronous cells or after the repair of the DNA damage (þHU/PW condition). Importantly, this interaction was increased following exposure of cells to HU (Figure 6A and B). These findings were supported by the increased colocalization of RAP80 and BLM in HU-treated cells (Figure 6C).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-fibroblast) taxid:9606(Homo sapiens diploid fibroblast) |
| Parameters of the interaction | - |
| Creation date | 2013/10/17 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |