Curation Details
Interaction ID: IM-21648-6

Unique identifier for interactor Auniprotkb:Q13526
Unique identifier for interactor Buniprotkb:Q13950
Alternative identifier for interactor Aintact:EBI-714158
uniprotkb:Q53X75
uniprotkb:A8K4V9
ensembl:ENSP00000247970.5
ensembl:ENSP00000466962.1
Alternative identifier for interactor Bintact:EBI-976402
intact:EBI-28971669
uniprotkb:O14614
uniprotkb:O14615
uniprotkb:O95181
ensembl:ENSP00000360493.1
ensembl:ENSP00000495497.1
Aliases for Apsi-mi:pin1_human(display_long)
uniprotkb:Rotamase Pin1(gene name synonym)
uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)
uniprotkb:PIN1(gene name)
psi-mi:PIN1(display_short)
Aliases for Bpsi-mi:runx2_human(display_long)
uniprotkb:Oncogene AML-3(gene name synonym)
uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)
uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)
uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)
uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)
uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)
uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)
uniprotkb:RUNX2(gene name)
psi-mi:RUNX2(display_short)
uniprotkb:AML3(gene name synonym)
uniprotkb:CBFA1(gene name synonym)
uniprotkb:OSF2(gene name synonym)
uniprotkb:PEBP2A(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorLee et al. (2013)
Identifier of the publicationimex:IM-21648
pubmed:24113655
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8772481
imex:IM-21648-6
Confidence scoreintact-miscore:0.59
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3c
comment:"\". Lysates of Runx2 transfected cells were incubated with or without calf intestinal alkaline phosphatase (CIP) and subjected to immunoprecipitation. Dephosphorylation of Runx2 abolished the binding between Runx2 and Pin1 (Fig. 2D). These results indicate that Pin1 interacts with Runx2 in Runx2 phosphorylation-dependent manner.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293a)
taxid:9606(Homo sapiens HEK293A embryonic kidney cell)
Parameters of the interaction-
Creation date2013/09/25
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Axpress tag:?-?
mutation disrupting interaction:16-16
Feature(s) for interactor Bmyc tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BAnti tag western blot