Curation Details
Interaction ID: IM-21646-2

Unique identifier for interactor Auniprotkb:P67775
Unique identifier for interactor Buniprotkb:Q9Y2T4
Alternative identifier for interactor Aintact:EBI-712311
ensembl:ENSP00000418447.1
uniprotkb:P05323
uniprotkb:P13197
Alternative identifier for interactor Bintact:EBI-1774058
uniprotkb:A8MSY7
uniprotkb:Q7Z4V7
uniprotkb:Q8NEC4
uniprotkb:B7Z3Y1
ensembl:ENSP00000372042.4
uniprotkb:Q9H3G7
Aliases for Apsi-mi:pp2aa_human(display_long)
uniprotkb:PPP2CA(gene name)
psi-mi:PPP2CA(display_short)
uniprotkb:Replication protein C(gene name synonym)
Aliases for Bpsi-mi:2abg_human(display_long)
uniprotkb:PPP2R2C(gene name)
psi-mi:PPP2R2C(display_short)
uniprotkb:PP2A subunit B isoform gamma(gene name synonym)
uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)
uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)
uniprotkb:IMYPNO1(gene name synonym)
uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorFan et al. (2013)
Identifier of the publicationimex:IM-21646
pubmed:24126060
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8764792
imex:IM-21646-2
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3d
comment:"\"We next investigated whether S6K is a direct target of B55 Gamma. Out of our expectations, however, B55 gamma did not interact with S6K (Fig.3D left & middle) in U87 B55 Gamma and other glioma cell lines (data not shown). But it was still interesting that although B55 gamma did not bind with S6K, overexpression of B55 gamma enhanced the binding of PP2A catalytic subunit with S6K (Fig.3D middle & right). T\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-u87)
taxid:9606(Homo sapiens U-87 MG glioblastoma cell)
Parameters of the interaction-
Creation date2013/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmyc tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot