| Unique identifier for interactor A | uniprotkb:O95292 |
| Unique identifier for interactor B | uniprotkb:O95070 |
| Alternative identifier for interactor A | intact:EBI-1188298 ensembl:ENSP00000417175.1 uniprotkb:O95293 uniprotkb:Q9P0H0 uniprotkb:A2A2F2 |
| Alternative identifier for interactor B | intact:EBI-2799703 uniprotkb:Q9BVD0 uniprotkb:A6NM00 uniprotkb:Q96G83 ensembl:ENSP00000366098.4 |
| Aliases for A | psi-mi:vapb_human(display_long) uniprotkb:VAPB(gene name) psi-mi:VAPB(display_short) uniprotkb:UNQ484/PRO983(orf name) |
| Aliases for B | psi-mi:yif1a_human(display_long) uniprotkb:54TM(gene name synonym) uniprotkb:HYIF1P(gene name synonym) uniprotkb:YIF1(gene name synonym) uniprotkb:54TMp(gene name synonym) uniprotkb:YIP1-interacting factor homolog A(gene name synonym) uniprotkb:YIF1A(gene name) psi-mi:YIF1A(display_short) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Kuijpers et al. (2013) |
| Identifier of the publication | imex:IM-21642 pubmed:23736259 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8804463 imex:IM-21642-2 |
| Confidence score | intact-miscore:0.60 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f1b f2f f2g f2i comment:"\"Pull-down experiments with biotinylated VAPB showed that all transmembrane containing YIF1A constructs co-precipitated with VAPB (Figure 2F). However, VAPB brings down considerable higher amounts of truncated GFP-YIF1A proteins that contain the first and second transmembrane domain (131–198) (Figure 2F), indicating that the VAPB interaction is strongest with this region. The marked difference between binding of the first two transmembrane domains compared to the last two transmembrane domains suggests a specific interaction between YIF1A and VAPB. GFP-YIF1A (131–198) also efficiently co-precipitated with VAPB-P56S (Figure 2G).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens HEK293T embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2013/10/17 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | biotin tag:?-? ha tag:?-? |
| Feature(s) for interactor B | green fluorescent protein tag:?-? binding-associated region:131-198 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |