Curation Details
Interaction ID: IM-21577-2

Unique identifier for interactor Auniprotkb:O08623
Unique identifier for interactor Buniprotkb:P19490
Alternative identifier for interactor Aintact:EBI-2935892
uniprotkb:Q8CH59
ensembl:ENSRNOP00000056021.3
ensembl:ENSRNOP00055026330
ensembl:ENSRNOP00060027499
ensembl:ENSRNOP00065006759
Alternative identifier for interactor Bintact:EBI-371642
ensembl:ENSRNOP00000064722.3
ensembl:ENSRNOP00055042480
ensembl:ENSRNOP00060032516
ensembl:ENSRNOP00065007367
Aliases for Apsi-mi:sqstm_rat(display_long)
uniprotkb:Sqstm1(gene name)
psi-mi:Sqstm1(display_short)
uniprotkb:Zip(gene name synonym)
uniprotkb:Protein kinase C-zeta-interacting protein(gene name synonym)
uniprotkb:Ubiquitin-binding protein p62(gene name synonym)
Aliases for Bpsi-mi:gria1_rat(display_long)
uniprotkb:Gria1(gene name)
psi-mi:Gria1(display_short)
uniprotkb:GluR-A(gene name synonym)
uniprotkb:GluR-K1(gene name synonym)
uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)
uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)
uniprotkb:Glur1(gene name synonym)
uniprotkb:GluA1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorRen et al. (2013)
Identifier of the publicationpubmed:23511975
imex:IM-21577
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8795268
imex:IM-21577-2
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4c sf14
comment:"\"Then, we employed anti-GluA1 antibody to precipitate the protein complex and to examine how PI3K activation would affect the association between these molecules. We found that upon 740Y-P treatment the amounts of p62 and PKCl that interacted with GluA1 (p62/GluA1 and PKCl/ GluA1) were significantly increased (Figures 4A and B), and the amount of P-Ser818-GluA1 was also increased simultaneously (Figures 4A and B).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:10116(rat-hippocampus)
taxid:10116(Rattus norvegicus hippocampal neurons)
Parameters of the interaction-
Creation date2013/10/15
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot