Curation Details
Interaction ID: IM-21408-14

Unique identifier for interactor Auniprotkb:P49736
Unique identifier for interactor Buniprotkb:P25205
Alternative identifier for interactor Aintact:EBI-374819
ensembl:ENSP00000265056.7
uniprotkb:Q14577
uniprotkb:Q15023
uniprotkb:Q8N2V1
uniprotkb:Q969W7
uniprotkb:Q96AE1
uniprotkb:Q9BRM7
Alternative identifier for interactor Bintact:EBI-355153
ensembl:ENSP00000472940.2
uniprotkb:B4DWW4
uniprotkb:Q92660
uniprotkb:Q9BTR3
uniprotkb:Q9NUE7
Aliases for Apsi-mi:mcm2_human(display_long)
uniprotkb:MCM2(gene name)
psi-mi:MCM2(display_short)
uniprotkb:BM28(gene name synonym)
uniprotkb:CDCL1(gene name synonym)
uniprotkb:KIAA0030(gene name synonym)
uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)
uniprotkb:Nuclear protein BM28(gene name synonym)
uniprotkb:CCNL1(gene name synonym)
Aliases for Bpsi-mi:mcm3_human(display_long)
uniprotkb:MCM3(gene name)
psi-mi:MCM3(display_short)
uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)
uniprotkb:RLF subunit beta(gene name synonym)
uniprotkb:p102(gene name synonym)
uniprotkb:P1-MCM3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0029"(cosedimentation through density gradient)
First authorNguyen et al. (2012)
Identifier of the publicationpubmed:22540012
imex:IM-21408
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8756364
imex:IM-21408-14
Confidence scoreintact-miscore:0.92
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4
comment:"\"To know the interaction of MCM2-7 complex with MCM-BP, purified these proteins were incubated and then fractionated by glycerol gradient centrifugation (Fig. 4). First, when the purified MCM2-7 complex was incubated in the absence of MCM-BP and then fractionated, MCM2-7 proteins were mainly co-sedimented at fraction no. 4 and 5, although MCM3 and MCM6 were not distinctly identified (top). The position of the sedimentation suggests that MCM2-7 proteins mainly form a heterohexamer\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2013/09/09
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot