| Unique identifier for interactor A | uniprotkb:O75419 |
| Unique identifier for interactor B | uniprotkb:P15927 |
| Alternative identifier for interactor A | intact:EBI-374969 uniprotkb:O60856 uniprotkb:Q6UW54 uniprotkb:Q9UP68 uniprotkb:Q20WK8 uniprotkb:B4DDB4 uniprotkb:B4DDU3 uniprotkb:E9PDH7 ensembl:ENSP00000263201.2 |
| Alternative identifier for interactor B | intact:EBI-621404 uniprotkb:Q52II0 uniprotkb:Q5TEI9 uniprotkb:Q5TEJ5 ensembl:ENSP00000363021.3 |
| Aliases for A | psi-mi:cdc45_human(display_long) uniprotkb:CDC45(gene name) psi-mi:CDC45(display_short) uniprotkb:CDC45L2(gene name synonym) uniprotkb:UNQ374/PRO710(orf name) uniprotkb:PORC-PI-1(gene name synonym) uniprotkb:CDC45L(gene name synonym) |
| Aliases for B | psi-mi:rfa2_human(display_long) uniprotkb:RPA34(gene name synonym) uniprotkb:Replication protein A 34 kDa subunit(gene name synonym) uniprotkb:Replication factor A protein 2(gene name synonym) uniprotkb:RPA2(gene name) psi-mi:RPA2(display_short) uniprotkb:REPA2(gene name synonym) uniprotkb:RPA32(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Broderick et al. (2013) |
| Identifier of the publication | pubmed:23910567 imex:IM-21321 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-6914803 imex:IM-21321-6 |
| Confidence score | intact-miscore:0.58 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f3c comment:"\"similar amounts of FLAG-Cdc45 were immunoprecipitated from extracts of these elutriated cells (Figure 3C). From these elutriated cells, FLAG-Cdc45 bound a maximal amount of p125 of Pol δ from extracts of cells enriched in S phase (Figure 3C), which is consistent with previously described findings studying thymidine-arrested and released cells [19]. These results supported the functional activity of the FLAG-Cdc45. The western blots of the FLAG-affinity pull-downs showed that FLAG-Cdc45 co- immunoprecipitated Claspin and RPA32 maximally from cells enriched in S phase of the cell cycle (Figure 3C).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-k_562) taxid:9606(Homo sapiens K562 myeloid leukemia cell) |
| Parameters of the interaction | - |
| Creation date | 2013/08/04 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |