Curation Details
Interaction ID: IM-15073-3

Unique identifier for interactor Auniprotkb:P16104
Unique identifier for interactor Buniprotkb:Q9Z0X1-PRO_0000022031
Alternative identifier for interactor Aintact:EBI-494830
uniprotkb:Q4ZGJ7
uniprotkb:Q6IAS5
ensembl:ENSP00000364310.1
ensembl:ENSP00000434024.1
Alternative identifier for interactor Bintact:EBI-5326677
Aliases for Apsi-mi:h2ax_human(display_long)
uniprotkb:H2AX(gene name)
psi-mi:H2AX(display_short)
uniprotkb:H2AFX(gene name synonym)
uniprotkb:Histone H2A.X(gene name synonym)
Aliases for Bpsi-mi:q9z0x1-pro_0000022031(display_long)
uniprotkb:Aifm1(gene name)
psi-mi:Aifm1(display_short)
uniprotkb:Aif(gene name synonym)
uniprotkb:Pdcd8(gene name synonym)
uniprotkb:Programmed cell death protein 8(gene name synonym)
Interaction detection methodspsi-mi:"MI:0107"(surface plasmon resonance)
First authorArtus et al. (2010)
Identifier of the publicationpubmed:20360685
mint:MINT-7893744
imex:IM-15073
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-5326687
imex:IM-15073-3
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:2a
kinetics:Dissociation of the tAIF/H2AX complex shows two phases, one slow and one fast.
dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:8.7x10^-7 ~2.2(molar)
koff:6.5x10^-2(second -1)
koff:1.29x10^-3(second -1)
Creation date2010/05/14
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:n-n
Feature(s) for interactor Bhis tag:n-n
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant