| Unique identifier for interactor A | uniprotkb:Q07817-1 |
| Unique identifier for interactor B | uniprotkb:Q14457 |
| Alternative identifier for interactor A | intact:EBI-287195 ensembl:ENSP00000302564.4 ensembl:ENSP00000365230.2 ensembl:ENSP00000389688.2 ensembl:ENSP00000390760.2 ensembl:ENSP00000395545.2 ensembl:ENSP00000401173.2 ensembl:ENSP00000503725.1 ensembl:ENSP00000504237.1 ensembl:ENSP00000504387.1 ensembl:ENSP00000504536.1 intact:EBI-8058735 intact:MINT-89566 intact:EBI-8058554 intact:EBI-8058512 intact:EBI-8058443 |
| Alternative identifier for interactor B | intact:EBI-949378 ensembl:ENSP00000355231.3 ensembl:ENSP00000465364.1 uniprotkb:B2R6N7 intact:EBI-28978189 uniprotkb:O75595 uniprotkb:Q9UNA8 |
| Aliases for A | psi-mi:q07817-1(display_long) uniprotkb:BCLX(gene name synonym) uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) uniprotkb:BCL2L1(gene name) psi-mi:BCL2L1(display_short) uniprotkb:BCL2L(gene name synonym) uniprotkb:Bcl-xL(isoform synonym) |
| Aliases for B | psi-mi:becn1_human(display_long) uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym) uniprotkb:Protein GT197(gene name synonym) uniprotkb:BECN1(gene name) psi-mi:BECN1(display_short) uniprotkb:GT197(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0053"(fluorescence polarization spectroscopy) |
| First author | Maiuri et al. (2007) |
| Identifier of the publication | pubmed:17446862 imex:IM-11145 mint:MINT-5219870 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-5235017 imex:IM-11145-5 |
| Confidence score | intact-miscore:0.70 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Competitor |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:1d and 2a antagonist:BH3 domain mimetic compound ABT737 disrupts the interaction in a dose-dependent manner. dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kd:2.036x10^-7(molar) ic50:1.7x10^-6(molar) |
| Creation date | 2007/07/11 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | glutathione s tranferase tag:n-n sufficient binding region:1-208 mutation disrupting interaction:138-138 |
| Feature(s) for interactor B | fluorescein label:?-? sufficient binding region:107-132 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |