Curation Details
Interaction ID: IM-11145-10

Unique identifier for interactor Auniprotkb:Q92934
Unique identifier for interactor Buniprotkb:P10415
Alternative identifier for interactor Aintact:EBI-700771
uniprotkb:O14803
uniprotkb:Q6FH21
ensembl:ENSP00000309103.3
ensembl:ENSP00000378040.3
Alternative identifier for interactor Bintact:EBI-77694
uniprotkb:P10416
uniprotkb:Q13842
uniprotkb:Q16197
uniprotkb:C9JHD5
ensembl:ENSP00000329623.3
ensembl:ENSP00000381185.1
Aliases for Apsi-mi:bad_human(display_long)
uniprotkb:Bcl-2-binding component 6(gene name synonym)
uniprotkb:Bcl-2-like protein 8(gene name synonym)
uniprotkb:BAD(gene name)
psi-mi:BAD(display_short)
uniprotkb:BBC6(gene name synonym)
uniprotkb:BCL2L8(gene name synonym)
uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)
uniprotkb:Bcl2 antagonist of cell death(gene name synonym)
Aliases for Bpsi-mi:bcl2_human(display_long)
uniprotkb:BCL2(gene name)
psi-mi:BCL2(display_short)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorMaiuri et al. (2007)
Identifier of the publicationpubmed:17446862
imex:IM-11145
mint:MINT-5219870
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-5241997
imex:IM-11145-10
Confidence scoreintact-miscore:0.85
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:7c
antagonist:BH3 domain mimetic compound ABT737 and starvation conditions disrupt the interaction.
dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2007/07/11
Update date2024/11/06
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot